Bubble-graft coverage after Descemet Membrane Endothelial Keratoplasty depending on gaze angle

• Verfasst von: Friedrich, Maximilian [VerfasserIn]
• Verfasst von: Son, Hyeck Soo [VerfasserIn]
• Verfasst von: Buhl, Rebecca [VerfasserIn]
• Verfasst von: Meyer, Christine Maria [VerfasserIn]
• Verfasst von: Yildirim, Timur Mert [VerfasserIn]
• Verfasst von: Khoramnia, Ramin [VerfasserIn]
• Verfasst von: Auffarth, Gerd U. [VerfasserIn]
• Verfasst von: Augustin, Victor A. [VerfasserIn]
• Titel: Bubble-graft coverage after Descemet Membrane Endothelial Keratoplasty depending on gaze angle
• Verf.angabe: Maximilian Friedrich, Hyeck-Soo Son, Rebecca Charlotte Buhl, Christine Maria Meyer, Timur Mert Yildirim, Ramin Khoramnia, Gerd Uwe Auffarth, and Victor Aristide Augustin
• Ausgabe: Online first
• E-Jahr: 2024
• Jahr: August 9, 2024
• Umfang: 7 S.
• Illustrationen: Illustrationen
• Fussnoten: Gesehen am 13.01.2025
• Titel Quelle: Enthalten in: European journal of ophthalmology
• Ort Quelle: Thousand Oaks, CA : Sage Publishing, 1991
• Jahr Quelle: 2024
• Band/Heft Quelle: (2024), online first, Seite 1-7
• ISSN Quelle: 1724-6016
• DOI: doi:10.1177/11206721241267277
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1914419421

Abstract

Purpose - In Descemet Membrane Endothelial Keratoplasty (DMEK) a gas bubble is usually used to attach the graft to the host cornea. In this study, we observed the bubble size and bubble-graft coverage at different gaze angles following DMEK. - Methods - This observational prospective study analyzed 465 images of patients who underwent an uneventful DMEK. Intraoperatively, the anterior chamber was filled up to 90% of its volume with a 20% Sulfur Hexafluoride (SF6) gas-air mixture. Postoperatively, the bubble was photographed daily in different gaze angles ranging from a supine position (0°) to an upright position (90°) and a slightly inclined position (105°). The primary outcomes were bubble-graft coverage and bubble diameters depending on the gaze angle and time after DMEK. - Results - The highest bubble-graft coverage was achieved at a 0° gaze angle at all times of measurement. In the first 48 h after DMEK, the mean bubble-graft coverage was over 85% at a gaze angle between 0° and 45°. Starting 72 h after DMEK, the graft coverage declined at all gaze angles. The graft coverage at a 0° gaze angle was 88.61 ± 10.90% after 96 postoperative hours, while the graft coverage was below 85% at all other gaze angles. - Conclusion - Our clinical results provide novel insight into variation in bubble-graft coverage as a function of gaze angle and may be used to aid in patient counselling for appropriate body positioning following DMEK to prevent early graft detachment. Maintaining supine positioning seems to be most advantageous starting 48 h after DMEK.