| |  Online-Ressource |
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| Verfasst von: | Maurer, Martin H. [VerfasserIn]  |
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| | Feldmann, Robert Enrico [VerfasserIn] |
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| | Fütterer, Carsten Dietmar [VerfasserIn] |
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| | Butlin, Jo [VerfasserIn] |
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| | Kuschinsky, Wolfgang [VerfasserIn] |
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| Titel: | Erratum: Comprehensive proteome expression profiling of undifferentiated versus differentiated neural stem cells from adult rat hippocampus |
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| Verf.angabe: | Martin H. Maurer, Robert E. Feldmann, Carsten D. Fütterer, Jo Butlin, and Wolfgang Kuschinsky |
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| E-Jahr: | 2005 |
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| Jahr: | January 2005 |
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| Umfang: | 2 S. |
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| Fussnoten: | Gesehen am 14.01.2025 |
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| Titel Quelle: | Enthalten in: Neurochemical research |
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| Ort Quelle: | Dordrecht [u.a.] : Springer Science + Business Media B.V, 1976 |
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| Jahr Quelle: | 2005 |
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| Band/Heft Quelle: | 30(2005), 1 vom: Jan., Seite 159-160 |
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| ISSN Quelle: | 1573-6903 |
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| Abstract: | Adult neural stem cells can be isolated from various regions of the rat brain and seem to have multilineage differentiation potential. In this study, we investigated the hypothesis that global protein expression of adult neural stem cells isolated from rat hippocampus is changed during in vitro differentiation. After 2 days of differentiation, we separated total protein extracts by two-dimensional gel electrophoresis and used mass spectrometry and gel-matching for identification. We detected a differential expression in 367 regulated protein spots, of which 128 could be identified. Regulated proteins included participants in transcription and DNA metabolism; signal transduction and Ca2+-signaling; MAP kinase pathways; cytoskeletal rearrangement; regulation of cell cycle, proliferation, and survival; protein biosynthesis, folding, and degradation; and glycine and glutamate metabolic pathways. These results suggest a massive reorganization of the stem cell proteomic profile upon differentiation and indicate potential cellular targets mediating the differentiation of neural stem cells. |
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| DOI: | doi:10.1007/s11064-004-0543-1 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1007/s11064-004-0543-1 |
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| | Volltext: https://link.springer.com/article/10.1007/s11064-004-0543-1 |
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| | DOI: https://doi.org/10.1007/s11064-004-0543-1 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Bibliogr. Hinweis: | Errata zu: Maurer, Martin H., 1971 - : Comprehensive proteome expression profiling of undifferentiated versus differentiated neural stem cells from adult rat hippocampus |
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| K10plus-PPN: | 1914538560 |
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| Verknüpfungen: | → Zeitschrift |
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Erratum: Comprehensive proteome expression profiling of undifferentiated versus differentiated neural stem cells from adult rat hippocampus / Maurer, Martin H. [VerfasserIn]; January 2005 (Online-Ressource)
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