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Status: Bibliographieeintrag

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Verfasst von:Hasse, Felix [VerfasserIn]   i
 Giannakis, Athanasios [VerfasserIn]   i
 Wehrse, Eckhard [VerfasserIn]   i
 Stiller, Wolfram [VerfasserIn]   i
 Wallwiener, Markus [VerfasserIn]   i
 Kauczor, Hans-Ulrich [VerfasserIn]   i
 Weber, Tim [VerfasserIn]   i
 Heil, Jörg [VerfasserIn]   i
 Mokry, Theresa [VerfasserIn]   i
Titel:Improvement of breast cancer detection using dual-layer spectral CT
Verf.angabe:Felix Christian Hasse, Athanasios Giannakis, Eckhard Wehrse, Wolfram Stiller, Markus Wallwiener, Hans-Ulrich Kauczor, Tim F. Weber, Jörg Heil and Theresa Mokry
E-Jahr:2024
Jahr:19 July 2024
Umfang:11 S.
Illustrationen:Illustrationen
Fussnoten:Gesehen am 15.01.2025
Titel Quelle:Enthalten in: Diagnostics
Ort Quelle:Basel : MDPI, 2011
Jahr Quelle:2024
Band/Heft Quelle:14(2024), 14, Artikel-ID 1560, Seite 1-11
ISSN Quelle:2075-4418
Abstract:This study aimed to investigate the diagnostic performance of breast mass detection on monoenergetic image data at 40 keV (MonoE40) and on iodine maps (IM) compared with conventional image data (CI). In this prospective single-center case-control study, 50 breast cancer patients were examined using contrast-enhanced dual-layer spectral CT. For qualitative and quantitative comparison of MonoE40 and IM with CI image data, four blinded, independent readers assessed 300 randomized single slices (two slices for each imaging type per case) with or without cancerous lesions for the presence of a breast mass. Detection sensitivity and specificity were calculated and readers rated their subjective diagnostic certainty. For statistical analysis of sensitivity and specificity, a paired t-test and ANOVA were used (significance level p = 0.05). A total of 50 female patients (median age 51 years, range 28-83 years) participated. IM had the highest overall scores in sensitivity and specificity for breast cancer detection, with 0.97 ± 0.06 and 0.95 ± 0.07, respectively, compared with 0.90 ± 0.04 and 0.92 ± 0.06 in CI. MonoE40 yielded a sensitivity of 0.96 ± 0.02 and specificity of 0.94 ± 0.08. All differences in sensitivity and specificity between MonoE or IM and CI were statistically significant (p < 0.001). The superiority of IM sensitivity and specificity was most pronounced in patients with dense breasts. Spectral CT improved the detection of breast cancer with higher sensitivity and specificity compared to conventional image data in our study.
DOI:doi:10.3390/diagnostics14141560
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

kostenfrei: Volltext: https://doi.org/10.3390/diagnostics14141560
 kostenfrei: Volltext: https://www.mdpi.com/2075-4418/14/14/1560
 DOI: https://doi.org/10.3390/diagnostics14141560
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:breast neoplasms
 multidetector computed tomography
 thorax
K10plus-PPN:1914743652
Verknüpfungen:→ Zeitschrift

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