| |  Online-Ressource |
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| Verfasst von: | Li, Xiaoguang [VerfasserIn]  |
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| | Pas, Hendri H [VerfasserIn] |
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| | Qian, Hua [VerfasserIn] |
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| | Rashid, Hanan [VerfasserIn] |
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| | Horvath, Barbara [VerfasserIn] |
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| | Yilmaz, Osman K. [VerfasserIn] |
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| | Beek, Nina van [VerfasserIn] |
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| | Schmidt, Enno [VerfasserIn] |
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| | Zillikens, Detlef [VerfasserIn] |
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| | Ishii, Norito [VerfasserIn] |
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| | Tsuruta, Daisuke [VerfasserIn] |
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| | Hashimoto, Takashi [VerfasserIn] |
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| Titel: | Potential correlation between anti-laminin 332 autoantibodies and malignant tumours in anti-BP180-type mucous membrane pemphigoid |
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| Verf.angabe: | Xiaoguang Li, Hendri H Pas, Hua Qian, Hanan Rashid, Barbara Horvath, Kaan Yilmaz, Nina van Beek, Enno Schmidt, Detlef Zillikens, Norito Ishii, Daisuke Tsuruta, Takashi Hashimoto |
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| E-Jahr: | 2024 |
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| Jahr: | September 2024 |
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| Umfang: | 2 S. |
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| Fussnoten: | Online veröffentlicht: 18. April 2024 ; Gesehen am 22.01.2025 |
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| Titel Quelle: | Enthalten in: Clinical and experimental dermatology |
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| Ort Quelle: | Kettering : Oxford University Press, 1976 |
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| Jahr Quelle: | 2024 |
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| Band/Heft Quelle: | 49(2024), 9 vom: Sept., Seite 1075-1076 |
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| ISSN Quelle: | 1365-2230 |
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| Abstract: | Dear Editor, Several studies have indicated a correlation between the presence of malignant tumours and anti-laminin 332 (LM332)-type mucous membrane pemphigoid (MMP),1,2 in contrast to the absence of such a correlation in patients with anti-BP180-type MMP (BP180-MMP).3 It has been observed that anti-LM332 autoantibodies may also be present in patients with BP180-MMP.3 In the present study, we assessed the relationship between anti-LM332 autoantibodies and the incidence of malignant tumours in patients with BP180-MMP.We recruited 520 patients with BP180-MMP, including 331 patients from Japan, 19 from China, 108 from the Netherlands and 62 from Germany. Essential criteria for BP180-MMP diagnosis include reactivity with the epidermal side in indirect immunofluorescence using 1 M NaCl split skin, positivity for anti-BP180 autoantibodies in immunoblotting of epidermal extract, and/or immunoblotting and/or enzyme-linked immunosorbent assay of recombinant proteins of BP180 NC16a and/or C-terminal domains. The detection of anti-LM332 autoantibodies was conducted utilizing various methods among multiple cohorts: by immunoblotting of purified LM332 or its recombinant protein in the Japanese and Chinese cohorts;1,3 by keratinocyte footprint assay in the Dutch cohort;4 by indirect immunofluorescence (Biochip® Mosaic; EUROIMMUN, Lübeck, Germany)2,4 and immunoblotting of keratinocyte-derived LM332 in the German cohort. |
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| DOI: | doi:10.1093/ced/llae124 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1093/ced/llae124 |
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| | DOI: https://doi.org/10.1093/ced/llae124 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| K10plus-PPN: | 1915400856 |
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| Verknüpfungen: | → Zeitschrift |
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Potential correlation between anti-laminin 332 autoantibodies and malignant tumours in anti-BP180-type mucous membrane pemphigoid / Li, Xiaoguang [VerfasserIn]; September 2024 (Online-Ressource)
