Navigation überspringen
Universitätsbibliothek Heidelberg
Status: Bibliographieeintrag

Verfügbarkeit
Standort: ---
Exemplare: ---
heiBIB
 Online-Ressource
Verfasst von:Yücel, Gökhan [VerfasserIn]   i
 Gaasch, Leo [VerfasserIn]   i
 Kodeih, Abbass [VerfasserIn]   i
 Hetjens, Svetlana [VerfasserIn]   i
 Yazdani, Babak [VerfasserIn]   i
 Pfleger, Stefan [VerfasserIn]   i
 Dürschmied, Daniel [VerfasserIn]   i
 Abraham, William T. [VerfasserIn]   i
 Akın, Ibrahim [VerfasserIn]   i
 Kuschyk, Jürgen [VerfasserIn]   i
Titel:Device-therapy in chronic heart failure
Titelzusatz:cardiac contractility modulation versus cardiac resynchronization therapy
Verf.angabe:Goekhan Yuecel, Leo Gaasch, Abbass Kodeih, Svetlana Hetjens, Babak Yazdani, Stefan Pfleger, Daniel Duerschmied, William T. Abraham, Ibrahim Akin and Juergen Kuschyk
E-Jahr:2025
Jahr:February 2025
Umfang:11 S.
Fussnoten:Erstmals veröffentlicht: 29. September 2024 ; Gesehen am 27.01.2025
Titel Quelle:Enthalten in: European Society of CardiologyESC heart failure
Ort Quelle:Chichester : Wiley, 2014
Jahr Quelle:2025
Band/Heft Quelle:12(2025), 1 vom: Feb., Seite 456-466
ISSN Quelle:2055-5822
Abstract:Aims Cardiac implantable electrical devices such as cardiac resynchronization therapy with defibrillator (CRT-Ds) or cardiac contractility modulation (CCMs) are therapy options for patients with symptomatic heart failure (HF) and reduced left ventricular ejection fraction (LVEF) despite optimal medical treatment. As yet, a comparison between both devices has not been performed. Methods and results The Mannheim Cardiac Resynchronization Therapy Registry (MARACANA) and the Mannheim Cardiac Contractility Modulation Observational Study (MAINTAINED) included all patients who received CRTs or CCMs in our medical centre between 2012 and 2021. For the present analysis, we retrospectively compared patients provided with either CRT-Ds (n = 220) or CCMs with additional defibrillators (n = 105) regarding New York Heart Association classification (NYHA), LVEF, tricuspid annular plane systolic excursion (TAPSE), QRS-width and other HF modification aspects after 12 months. Before implantation, CCM patients presented with lower LVEF (23.6 ± 6.2 vs. 26.3 ± 6.5%) and worse NYHA (3.03 ± 0.47 vs. 2.81 ± 0.48, both P < 0.05), compared with CRT-D patients. Follow-up improvements in NYHA (2.43 ± 0.67 vs. 2.28 ± 0.72), LVEF (30.5 ± 10.7 vs. 35.2 ± 10.5%) and TAPSE (17.2 ± 5.2 vs. 17.1 ± 4.8 to 18.9 ± 3.4 vs. 17.3 ± 3.6 mm, each P < 0.05) were comparable. The intrinsic QRS-width was stable with CCM (109.1 ± 18 vs. 111.7 ± 19.7 ms, P > 0.05), while the paced QRS-width with CRT-D after 12 months was lower than intrinsic values at baseline (157.5 ± 16.5 vs. 139.2 ± 16 ms, P < 0.05). HF hospitalizations occurred more often for CCM than CRT-D patients (45.7 vs. 16.8%/patient years, odds ratio 4.2, P < 0.001). Conclusions Chronic heart failure patients could experience comparable 12-month improvements in functional status and ventricular reverse remodelling, with appropriately implanted CCMs and CRT-Ds. Differences in HF hospitalization rates may be due to the more advanced HF of CCM patients at implantation.
DOI:doi:10.1002/ehf2.15067
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

kostenfrei: Volltext: https://doi.org/10.1002/ehf2.15067
 kostenfrei: Volltext: http://onlinelibrary.wiley.com/doi/abs/10.1002/ehf2.15067
 DOI: https://doi.org/10.1002/ehf2.15067
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:CCM
 Chronic heart failure
 CIED
 CRT
K10plus-PPN:1915644658
Verknüpfungen:→ Zeitschrift

Permanenter Link auf diesen Titel (bookmarkfähig):  https://katalog.ub.uni-heidelberg.de/titel/69294438   QR-Code
zum Seitenanfang