| Online-Ressource |
Verfasst von: | Bian, Yiding [VerfasserIn]  |
| Deng, Mingming [VerfasserIn]  |
| Gao, Qian [VerfasserIn]  |
| Zhou, Guowu [VerfasserIn]  |
| Tong, Run [VerfasserIn]  |
| Zhao, Ling [VerfasserIn]  |
| Liu, Min [VerfasserIn]  |
| Sun, Jie [VerfasserIn]  |
| Dai, Huaping [VerfasserIn]  |
| Herth, Felix [VerfasserIn]  |
| Hou, Gang [VerfasserIn]  |
| Wang, Chen [VerfasserIn]  |
Titel: | The diagnostic efficiency and safety of transbronchial lung cryobiopsy using 1.1-mm cryoprobe in diagnosing interstitial lung disease |
Verf.angabe: | Yiding Bian, Mingming Deng, Qian Gao, Guowu Zhou, Run Tong, Ling Zhao, Min Liu, Jie Sun, Huaping Dai, Felix J.F. Herth, Gang Hou, Chen Wang |
E-Jahr: | 2024 |
Jahr: | 23 June 2024 |
Umfang: | 9 S. |
Illustrationen: | Illustrationen |
Fussnoten: | Gesehen am 31.01.2025 |
Titel Quelle: | Enthalten in: Lung |
Ort Quelle: | New York, NY : Springer, 1903 |
Jahr Quelle: | 2024 |
Band/Heft Quelle: | 202(2024), 5 vom: Okt., Seite 615-623 |
ISSN Quelle: | 1432-1750 |
Abstract: | INTRODUCTION: Transbronchial lung cryobiopsy (TBLC) is increasingly used to diagnose interstitial lung disease (ILD). The 1.1-mm cryoprobe has recently been available in clinical practice. The diagnostic yield and safety of TBLC using a 1.1-mm cryoprobe need to be confirmed. - METHODS: A prospective, randomized controlled trial was conducted in patients with suspected ILD and randomly assigned to 1.1-mm and 1.9-mm cryoprobe groups. The primary outcome was the diagnostic yield of multidisciplinary discussion. Secondary outcomes were sample quality and incidence of complications. The tension and stress effects during TBLC onto the target lobe caused by 1.1-mm and 1.9-mm cryoprobes were also evaluated using finite element analysis. - RESULTS: A total of 224 patients were enrolled. No significant differences were observed in the diagnostic yield (80.4% vs. 79.5%, p = 0.845) and sample quality scores (5.73 ± 0.64 vs. 5.66 ± 0.77; p = 0.324) between the 1.9-mm cryoprobe group and 1.1-mm cryoprobe group. The average surface areas of samples in 1.1-mm cryoprobe group were smaller, while no difference in sample weights was observed. A decreased incidence of moderate bleeding was found in the 1.1-mm cryoprobe group (17.0% vs. 6.2%, p = 0.027), while there was no difference in the incidence of the pneumothorax, there was a trend to higher rate of pneumothorax in 1.1-mm group. In finite element analysis, the 1.1-mm cryoprobe required the largest tension and produced the largest stress. - CONCLUSION: Compared with a 1.9-mm cryoprobe, there was no difference in specimen quality or diagnostic rate but smaller sample size with a 1.1-mm cryoprobe. There was a decreased risk of moderate bleeding, but a trend towards increased risk for pneumothorax with 1.1-mm cryoprobe. - TRAIL REGISTRATION: Clinicaltrials.gov identifier NCT04047667; registered August 4, 2019. |
DOI: | doi:10.1007/s00408-024-00713-2 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1007/s00408-024-00713-2 |
| DOI: https://doi.org/10.1007/s00408-024-00713-2 |
Datenträger: | Online-Ressource |
Sprache: | eng |
Sach-SW: | 1.1-mm cryoprobe |
| Aged |
| Biopsy |
| Bronchoscopy |
| Cryosurgery |
| Female |
| Finite Element Analysis |
| Hemorrhage |
| Humans |
| Interstitial lung disease |
| Lung |
| Lung Diseases, Interstitial |
| Male |
| Middle Aged |
| Pneumothorax |
| Prospective Studies |
| Transbronchial lung cryobiopsy |
K10plus-PPN: | 1916105114 |
Verknüpfungen: | → Zeitschrift |
¬The¬ diagnostic efficiency and safety of transbronchial lung cryobiopsy using 1.1-mm cryoprobe in diagnosing interstitial lung disease / Bian, Yiding [VerfasserIn]; 23 June 2024 (Online-Ressource)