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Verfasst von:Bian, Yiding [VerfasserIn]   i
 Deng, Mingming [VerfasserIn]   i
 Gao, Qian [VerfasserIn]   i
 Zhou, Guowu [VerfasserIn]   i
 Tong, Run [VerfasserIn]   i
 Zhao, Ling [VerfasserIn]   i
 Liu, Min [VerfasserIn]   i
 Sun, Jie [VerfasserIn]   i
 Dai, Huaping [VerfasserIn]   i
 Herth, Felix [VerfasserIn]   i
 Hou, Gang [VerfasserIn]   i
 Wang, Chen [VerfasserIn]   i
Titel:The diagnostic efficiency and safety of transbronchial lung cryobiopsy using 1.1-mm cryoprobe in diagnosing interstitial lung disease
Verf.angabe:Yiding Bian, Mingming Deng, Qian Gao, Guowu Zhou, Run Tong, Ling Zhao, Min Liu, Jie Sun, Huaping Dai, Felix J.F. Herth, Gang Hou, Chen Wang
E-Jahr:2024
Jahr:23 June 2024
Umfang:9 S.
Illustrationen:Illustrationen
Fussnoten:Gesehen am 31.01.2025
Titel Quelle:Enthalten in: Lung
Ort Quelle:New York, NY : Springer, 1903
Jahr Quelle:2024
Band/Heft Quelle:202(2024), 5 vom: Okt., Seite 615-623
ISSN Quelle:1432-1750
Abstract:INTRODUCTION: Transbronchial lung cryobiopsy (TBLC) is increasingly used to diagnose interstitial lung disease (ILD). The 1.1-mm cryoprobe has recently been available in clinical practice. The diagnostic yield and safety of TBLC using a 1.1-mm cryoprobe need to be confirmed. - METHODS: A prospective, randomized controlled trial was conducted in patients with suspected ILD and randomly assigned to 1.1-mm and 1.9-mm cryoprobe groups. The primary outcome was the diagnostic yield of multidisciplinary discussion. Secondary outcomes were sample quality and incidence of complications. The tension and stress effects during TBLC onto the target lobe caused by 1.1-mm and 1.9-mm cryoprobes were also evaluated using finite element analysis. - RESULTS: A total of 224 patients were enrolled. No significant differences were observed in the diagnostic yield (80.4% vs. 79.5%, p = 0.845) and sample quality scores (5.73 ± 0.64 vs. 5.66 ± 0.77; p = 0.324) between the 1.9-mm cryoprobe group and 1.1-mm cryoprobe group. The average surface areas of samples in 1.1-mm cryoprobe group were smaller, while no difference in sample weights was observed. A decreased incidence of moderate bleeding was found in the 1.1-mm cryoprobe group (17.0% vs. 6.2%, p = 0.027), while there was no difference in the incidence of the pneumothorax, there was a trend to higher rate of pneumothorax in 1.1-mm group. In finite element analysis, the 1.1-mm cryoprobe required the largest tension and produced the largest stress. - CONCLUSION: Compared with a 1.9-mm cryoprobe, there was no difference in specimen quality or diagnostic rate but smaller sample size with a 1.1-mm cryoprobe. There was a decreased risk of moderate bleeding, but a trend towards increased risk for pneumothorax with 1.1-mm cryoprobe. - TRAIL REGISTRATION: Clinicaltrials.gov identifier NCT04047667; registered August 4, 2019.
DOI:doi:10.1007/s00408-024-00713-2
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.1007/s00408-024-00713-2
 DOI: https://doi.org/10.1007/s00408-024-00713-2
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:1.1-mm cryoprobe
 Aged
 Biopsy
 Bronchoscopy
 Cryosurgery
 Female
 Finite Element Analysis
 Hemorrhage
 Humans
 Interstitial lung disease
 Lung
 Lung Diseases, Interstitial
 Male
 Middle Aged
 Pneumothorax
 Prospective Studies
 Transbronchial lung cryobiopsy
K10plus-PPN:1916105114
Verknüpfungen:→ Zeitschrift

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