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Status: Bibliographieeintrag

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Verfasst von:Daghmouri, Mohamed Aziz [VerfasserIn]   i
 Chaouch, Mohamed Ali [VerfasserIn]   i
 Deniau, Benjamin [VerfasserIn]   i
 Benayoun, Laurent [VerfasserIn]   i
 Krimi, Bassem [VerfasserIn]   i
 Gouader, Amine [VerfasserIn]   i
 Oweira, Hani [VerfasserIn]   i
Titel:Efficacy and safety of intraperitoneal ropivacaine in pain management following laparoscopic digestive surgery
Titelzusatz:A systematic review and meta-analysis of RCTs
Verf.angabe:Mohamed Aziz Daghmouri, MD, Mohamed Ali Chaouch, MD, Benjamin Deniau, MD, Laurent Benayoun, MD, Bassem Krimi, MD, Amine Gouader, MD, Hani Oweira, MD
E-Jahr:2024
Jahr:July 19, 2024
Umfang:15 S.
Illustrationen:Illustrationen
Fussnoten:Gesehen am 17.02.2025
Titel Quelle:Enthalten in: Medicine
Ort Quelle:Baltimore, Md. : Lippincott Williams & Wilkins, 1922
Jahr Quelle:2024
Band/Heft Quelle:103(2024), 29, Artikel-ID e38856, Seite 1-15
ISSN Quelle:1536-5964
Abstract:Background: - Managing postoperative pain effectively with an opioid-free regimen following laparoscopic surgery (LS) remains a significant challenge. Intraperitoneal instillation of ropivacaine has been explored for its potential to reduce acute postoperative pain, but its efficacy and safety are still under debate. This study aimed to evaluate the efficacy and safety of intraperitoneal instillation of ropivacaine for acute pain management following laparoscopic digestive surgery. - Methods: - We used PRISMA 2020 and a measurement tool to assess systematic reviews 2 guidelines to conduct this review. The random-effects model was adopted using Review Manager Version 5.4 for pooled estimates. - Results: - We retained 24 eligible RCTs involving 1705 patients (862 patients in the intraperitoneal instillation group and 843 patients in the control group). The intraperitoneal instillation group reduced total opioid consumption during the first 24 hours postoperatively (MD = −21.93 95% CI [−27.64, −16.23], P < .01), decreased pain scores at different time (4 hours, 8 hours, 12 hours and 24 hours), shorter the hospital stay (MD = −0.20 95% CI [−0.36, −0.05], P < .01), reduced the postoperative shoulder pain (MD = 0.18 95% CI [0.07, 0.44], P < .01), and decreased postoperative nausea and vomiting (MD = 0.47 95% CI [0.29, 0.77], P < .01). - Conclusion: - Intraperitoneal instillation of ropivacaine appears to be an effective component of multimodal pain management strategies following laparoscopic digestive surgery, significantly reducing opioid consumption and improving postoperative recovery markers. Despite these promising results, additional high-quality trials are needed to confirm the efficacy and safety of this approach. - Registration: - The registration number at PROSPERO was CRD42021279238.
DOI:doi:10.1097/MD.0000000000038856
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.1097/MD.0000000000038856
 Volltext: https://journals.lww.com/md-journal/fulltext/2024/07190/efficacy_and_safety_of_intraperitoneal_ropivacaine.21.aspx
 DOI: https://doi.org/10.1097/MD.0000000000038856
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:1917403887
Verknüpfungen:→ Zeitschrift

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