MR enhancement of brain lesions

• Verfasst von: Knauth, Michael [VerfasserIn]
• Verfasst von: Forsting, Michael [VerfasserIn]
• Verfasst von: Hartmann, Marius [VerfasserIn]
• Verfasst von: Heiland, Sabine [VerfasserIn]
• Verfasst von: Balzer, Th. [VerfasserIn]
• Verfasst von: Sartor, Klaus [VerfasserIn]
• Titel: MR enhancement of brain lesions
• Titelzusatz: increased contrast dose compared with magnetization transfer.
• Verf.angabe: M. Knauth, M. Forsting, M. Hartmann, S. Heiland, T. Balzer, K. Sartor
• E-Jahr: 1996
• Jahr: 1 Nov 1996
• Umfang: 7 S.
• Fussnoten: Gesehen am 19.02.2025
• Titel Quelle: Enthalten in: American journal of neuroradiology
• Ort Quelle: Oak Brook, Ill. : Soc., 1980
• Jahr Quelle: 1996
• Band/Heft Quelle: 17(1996), 10, Seite 1853-1859
• ISSN Quelle: 1936-959X
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1917608799

Abstract

PURPOSE To compare image contrast and lesion conspicuity of enhancing intracranial lesions obtained with T1-weighted and magnetization transfer T1-weighted spin-echo sequences after administration of standard (0.1 mmol/kg body weight) and triple doses of gadobutrol. - METHODS Twenty-four patients with a total of 34 enhancing intracranial lesions were studied with T1-weighted and magnetization transfer T1-weighted spin-echo MR imaging. An incremental dose technique was used with intravenous injections of 0.1 and 0.2 mmol/kg body weight gadobutrol. Lesion-to-white matter contrast and white matter-to-edema contrast were calculated. - RESULTS The lesion-to-white matter contrast of the magnetization transfer T1-weighted studies was significantly higher than that of the T1-weighted studies when identical doses of gadobutrol were compared. The lesion-to-white matter contrast was not significantly different on the triple-dose T1-weighted study and the standard-dose magnetization transfer T1-weighted study. Two lesions were visible only on the standard-dose magnetization transfer T1-weighted and the triple-dose studies. - CONCLUSION Standard-dose magnetization transfer T1-weighted and triple-dose T1-weighted spin-echo MR studies are equally well suited to increase the lesion-to-white matter contrast in patients with enhancing intracranial lesions. Triple-dose magnetization transfer T1-weighted studies further increase lesion-to-white matter contrast but do not show additional lesions.