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| Verfasst von: | Wiedenmayer, Nadine [VerfasserIn]  |
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| | Hogrefe, Katharina [VerfasserIn] |
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| | Mihalceanu, Silvia [VerfasserIn] |
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| | Winkler, Julia K. [VerfasserIn] |
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| | Enk, Alexander [VerfasserIn] |
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| Titel: | Case report: a novel high-dose intravenous immunoglobulin preparation for the treatment of severe pemphigus vulgaris failing standard therapy |
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| Verf.angabe: | Nadine Wiedenmayer, Katharina Hogrefe, Silvia Mihalceanu, Julia K. Winkler, Alexander H. Enk (Department of Dermatology, University Hospital Heidelberg) |
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| E-Jahr: | 2024 |
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| Jahr: | December 2024 |
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| Umfang: | 4 S. |
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| Illustrationen: | Illustrationen |
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| Fussnoten: | Gesehen am 26.02.2025 |
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| Titel Quelle: | Enthalten in: The journal of dermatology |
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| Ort Quelle: | Oxford [u.a.] : Wiley-Blackwell, 1974 |
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| Jahr Quelle: | 2024 |
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| Band/Heft Quelle: | 51(2024), 12 vom: Dez., Seite 1665-1668 |
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| ISSN Quelle: | 1346-8138 |
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| Abstract: | Pemphigus vulgaris (PV) is a severe autoimmune bullous dermatosis that is characterized by autoantibodies against epidermal adhesion proteins causing painful mucosal and skin blistering. Standard treatments for PV include corticosteroids, steroid-sparing immunosuppressants, or intravenous monoclonal anti-CD20-antibody therapy. The European guidelines suggest high-dose intravenous immunoglobulin (IVIg) therapy as a promising approach for severe or treatment-resistant cases. We report on a 65-year-old woman with severe and recurrent disease who achieved long-term disease stabilization with IVIg treatment. Because of recurrent fatigue and headache, the patient was switched to an alternative IVIg preparation with a novel manufacturing process, thus ensuring high purity and better tolerability. We observed excellent efficacy, yet side effects remained largely unchanged. Further studies are necessary to evaluate the long-term efficacy and tolerability of this new IVIg preparation. |
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| DOI: | doi:10.1111/1346-8138.17475 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
kostenfrei: Volltext: https://doi.org/10.1111/1346-8138.17475 |
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| | kostenfrei: Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1111/1346-8138.17475 |
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| | DOI: https://doi.org/10.1111/1346-8138.17475 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | adverse effects |
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| | autoimmune bullous dermatoses |
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| | intravenous immunoglobulins |
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| | IVIg |
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| | pemphigus vulgaris |
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| K10plus-PPN: | 1918584397 |
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| Verknüpfungen: | → Zeitschrift |
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Case report: a novel high-dose intravenous immunoglobulin preparation for the treatment of severe pemphigus vulgaris failing standard therapy / Wiedenmayer, Nadine [VerfasserIn]; December 2024 (Online-Ressource)
