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Status: Bibliographieeintrag

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Verfasst von:Gable, Dennis R. [VerfasserIn]   i
 Verhoeven, Eric [VerfasserIn]   i
 Trimarchi, Santi [VerfasserIn]   i
 Böckler, Dittmar [VerfasserIn]   i
 Milner, Ross [VerfasserIn]   i
 Dubenec, Steven [VerfasserIn]   i
 Silveira, Pierre [VerfasserIn]   i
 Weaver, Fred [VerfasserIn]   i
Titel:Endovascular treatment for thoracic aortic disease from the Global Registry for Endovascular Aortic Treatment
Verf.angabe:Dennis R. Gable, MD, Eric Verhoeven, MD, PhD, Santi Trimarchi, MD, PhD, Dittmar Böckler, MD, Ross Milner, MD, Steven Dubenec, MD, Pierre Silveira, MD, and Fred Weaver, MD, on behalf of the GREAT Investigators
E-Jahr:2024
Jahr:May 2024
Umfang:14 S.
Illustrationen:Illustrationen
Fussnoten:Online verfügbar 26 December 2023, Version des Artikels 18 April 2024 ; Gesehen am 10.03.2025
Titel Quelle:Enthalten in: Journal of vascular surgery
Ort Quelle:Amsterdam [u.a.] : Elsevier, 1984
Jahr Quelle:2024
Band/Heft Quelle:79(2024), 5 vom: Mai, Seite 1044-1056.e1
ISSN Quelle:1097-6809
Abstract:Objective - Global Registry for Endovascular Aortic Treatment (GREAT) is an international prospective multicenter registry collecting real-world data on performance of W. L. Gore thoracic and abdominal aortic endografts. This analysis evaluated the long-term differences in patient survival and device performance in patients undergoing thoracic endovascular aortic repair (TEVAR) for any thoracic aortic pathology. - Methods - From August 2010 to October 2016, 5014 patients were enrolled in GREAT. The population of interest was comprised of only patients treated for thoracic aortic pathologies. Through 5 years, primary outcomes were all-cause and aortic-related mortality, stroke, aortic rupture, endoleaks, migration, fracture, compression, paraplegia, and any reintervention through 5 years, grouped by pathology. Secondary outcomes were reintervention rate and freedom from serious device- and aortic-related events. - Results - The 578 patients with thoracic aortic pathologies enrolled in GREAT and identified for this analysis were categorized by common pathologies: thoracic aneurysm (n = 239), thoracic dissection (n = 203), arch (n = 26), and other (n = 110). The mean age of this population was 66.1 ± 12.8 years, and 64.7% were male. Procedure survival was 99.7%. In the overall group, at index procedure to 30 days and 31 days to 5 years, Kaplan-Meier estimates of freedom from all-cause mortality were 99.6% and 66.4%, respectively, and for aortic-related mortality were 97.7% and 94.6%, respectively. Aortic rupture rate was 0.5% (n = 3) at 30 days and 1.4% (n = 8) through 5 years. Stroke and spinal cord ischemic events were 1.9% (n = 11) and 1.6% (n = 9) at 30 days and at 5 years were 3.6% (n = 20), 0.5% (n = 3), respectively. Reinterventions were required in 7.3% (n = 42) at 30 days and 12.4% (n = 69) through 5 years. The number of patients with endoleaks at 30 days was 2.1% (n = 12): n = 3 (1.1%) for each of types IA, 1B, and II; n = 2 (0.3%) for type III; and n = 4 (0.7%) for unspecified. Through 5 years, the percentage of patients was 8.3% (n = 40): n = 15 (3.1%) for type IA; n = 10 (2.1%) for type IB; n = 11 (2.3%) for type II; and n = 9 (1.9%) for unspecified. One patient (0.2%) had stent migration at 30 days (aneurysm group); none were reported through 5 years. There were no incidents of stent compression or fracture from index procedure through 5 years. - Conclusions - Data herein demonstrates durability and support for treatment of thoracic aortic disease with the GORE TAG conformable thoracic stent graft, including no incidents of stent compression/fracture and high freedom from aortic-related mortality. The planned analysis of follow-up to 10 years in GREAT will be beneficial.
DOI:doi:10.1016/j.jvs.2023.12.040
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

kostenfrei: Volltext: https://doi.org/10.1016/j.jvs.2023.12.040
 kostenfrei: Volltext: https://www.sciencedirect.com/science/article/pii/S0741521423024412
 DOI: https://doi.org/10.1016/j.jvs.2023.12.040
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:Aortic dissection
 CTAG
 GREAT
 Thoracic endovascular aortic repair
K10plus-PPN:1919395199
Verknüpfungen:→ Zeitschrift

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