| Online-Ressource |
Verfasst von: | ten Winkel, Meike [VerfasserIn]  |
| Salama, Hussein [VerfasserIn]  |
| Timrott, Kai [VerfasserIn]  |
| Kleine, Moritz [VerfasserIn]  |
| Kleine-Doepke, Dennis [VerfasserIn]  |
| Raehder-Johnson, Stephanie [VerfasserIn]  |
| Meisel, Holger [VerfasserIn]  |
| Rahberi, Nuh N. [VerfasserIn]  |
| Abdelhadi, Schaima [VerfasserIn]  |
| Rückert, Felix [VerfasserIn]  |
| Reißfelder, Christoph [VerfasserIn]  |
| Honselmann, Kim C. [VerfasserIn]  |
| Braun, Ruediger [VerfasserIn]  |
| Faerber, Benedikt [VerfasserIn]  |
| Lapshyn, Hryhoriy [VerfasserIn]  |
| Keck, Tobias [VerfasserIn]  |
| Uhl, Waldemar [VerfasserIn]  |
| Belyaev, Orlin [VerfasserIn]  |
| Wellner, Ulrich F. [VerfasserIn]  |
| Bolm, Louisa [VerfasserIn]  |
Titel: | Patient-reported outcomes at three months after pancreatic surgery for benign and malignant diseases |
Titelzusatz: | prospective observational study |
Verf.angabe: | Meike ten Winkel, Hussein Salama, Kai Timrott, Moritz Kleine, Dennis Kleine-Doepke, Stephanie Raehder-Johnson, Holger Meisel, Nuh N. Rahberi, Schaima Abdelhadi, Felix Rückert, Christoph Reissfelder, Kim C. Honselmann, Ruediger Braun, Benedikt Faerber, Hryhoriy Lapshyn, Tobias Keck, Waldemar Uhl, Orlin Belyaev, Ulrich F. Wellner, Louisa Bolm |
E-Jahr: | 2024 |
Jahr: | March 2024 |
Umfang: | 9 S. |
Illustrationen: | Illustrationen |
Fussnoten: | Online verfügbar: 18. Januar 2024, Artikelversion: 27. Februar 2024 ; Gesehen am 12.03.2025 |
Titel Quelle: | Enthalten in: Pancreatology |
Ort Quelle: | Amsterdam : Elsevier, 2001 |
Jahr Quelle: | 2024 |
Band/Heft Quelle: | 24(2024), 2, Seite 314-322 |
ISSN Quelle: | 1424-3911 |
Abstract: | Background/objectives - Pancreatic surgery may have a long-lasting effect on patients’ health status and quality of life (QoL). We aim to evaluate patient-reported outcomes (PRO) 3 months after pancreatic surgery. - Methods - Patients scheduled for pancreatic surgery were enrolled in a prospective trial at five German centers. Patients completed PRO questionnaires (EQ-5D-5L, EORTC QLQ-PAN26, patient-reported happiness, and HADS-D), we report the first follow-up 3 months after surgery as an interim analysis. Statistical testing was performed using R software. - Results - From 2019 to 2022 203 patients were enrolled, a three-month follow-up questionnaire was available in 135 (65.5 %). 77 (57.9 %) underwent surgery for malignant disease. Patient-reported health status (EQ-5D-5L) was impaired in 4/5 dimensions (mobility, self-care, usual activities, pain, discomfort) for patients with malignant and 3/5 dimensions (mobility, self-care, usual activities) for patients with benign disease 3 months after surgery (p < 0.05). Patients with malignant disease reported an increase in depressive symptoms, patients with benign disease had a decrease in anxiety symptoms (HADS-D; depression: 5.00 vs 6.51, p = 0.002; anxiety: 8.04 vs. 6.34, p = 0.030). Regarding pancreatic-disease-specific symptoms (EORTC-QLQ-PAN26), patients with malignant disease reported increased problems with taste, weight loss, weakness in arms and legs, dry mouth, body image and troubling side effects at three months. Patients with benign disease indicated more weakness in arms and legs, troubling side effects but less future worries at three months. - Conclusion - Patient-reported outcomes of patients undergoing pancreatic surgery for benign vs. malignant disease show important differences. Patients with malignant tumors report more severely decreased quality of life 3 months postoperatively than patients with benign tumors. |
DOI: | doi:10.1016/j.pan.2024.01.007 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
kostenfrei: Volltext: https://doi.org/10.1016/j.pan.2024.01.007 |
| kostenfrei: Volltext: https://www.sciencedirect.com/science/article/pii/S142439032400022X |
| DOI: https://doi.org/10.1016/j.pan.2024.01.007 |
Datenträger: | Online-Ressource |
Sprache: | eng |
K10plus-PPN: | 1919621040 |
Verknüpfungen: | → Zeitschrift |
Patient-reported outcomes at three months after pancreatic surgery for benign and malignant diseases / ten Winkel, Meike [VerfasserIn]; March 2024 (Online-Ressource)