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Verfasst von:Braun, Julia [VerfasserIn]   i
 Arensmeyer, Jan Christian [VerfasserIn]   i
 Hausen, Annekristin [VerfasserIn]   i
 Stolz, Verena [VerfasserIn]   i
 Keller, Peter Sebastian [VerfasserIn]   i
 Amarell, Nicola [VerfasserIn]   i
 Lurje, Georg [VerfasserIn]   i
 Schäfer, Nico [VerfasserIn]   i
 Kalff, Jörg C. [VerfasserIn]   i
 von Websky, Martin W. [VerfasserIn]   i
Titel:A cross-sectional observational study of quality of life in adult short bowel syndrome patients
Titelzusatz:what role does autologous gut reconstruction play?
Verf.angabe:Julia Braun, MD, Jan Christian Arensmeyer, MD, Annekristin Hausen, MD, Verena Stolz, BSc, Peter Sebastian Keller, MD, Nicola Amarell, MD, Georg Lurje, MD, Nico Schäfer, MD, Jörg C. Kalff, MD, Martin W. von Websky, MD
E-Jahr:2025
Jahr:February 2025
Umfang:9 S.
Illustrationen:Illustrationen
Fussnoten:Zuerst veröffentlicht: 12. Dezember 2024 ; Gesehen am 13.03.2025
Titel Quelle:Enthalten in: Nutrition in clinical practice
Ort Quelle:Hoboken, NJ : Wiley, 1986
Jahr Quelle:2025
Band/Heft Quelle:40(2025), 1 vom: Feb., Seite 147-155
ISSN Quelle:1941-2452
Abstract:Background Intestinal failure (IF) describes a condition of insufficient absorption capacity and general function of the gastrointestinal tract and may necessitate long-term intravenous fluid and nutrient supplementation. Quality of life (QoL) may be reduced in these patients. The aim of the study was to analyze QoL by two tools (SBS-QoL and SF-12) to elucidate which parameters impact QoL in patients with IF. Methods QoL was assessed in a cohort of 105 patients with IF at a tertiary referral center for intestinal rehabilitation. Complete data for SBS-QoL and SF-12 were available in 44 of 81 surviving patients at a single time point for a cross-sectional analysis. Medical data, outcome parameters, and comorbidities (Charlson comorbidity index [CCI]) were extracted and entered in a prospective database for analysis and correlation with QoL assessment. Results Subscales of SBS-QoL and SF-12 highly correlated with each other (P = −0.64 for physical subscales; P = −0.75 for mental subscales). Significant differences in QoL were detected in patients with Messing Type I (end-jejunostomy) and Type III anatomy (ileocolonic anastomosis) (one-way ANOVA: P < 0.05). Performance of autologous gut reconstruction (AGR) was associated with significantly better physical QoL. CCI correlated significantly with QoL scores. Longer duration of illness resulted in higher QoL in SBS-QoL (reduction of 0.15 per month; P = 0.045). Conclusion Both SBS-QoL and SF-12 are useful to determine QoL in patients with IF. AGR was associated with improved QoL by changing SBS-related anatomy and function. Thus, AGR surgery should be included in the treatment plan whenever possible. Comorbidities should be addressed interdisciplinarily to improve QoL.
DOI:doi:10.1002/ncp.11253
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

kostenfrei: Volltext: https://doi.org/10.1002/ncp.11253
 kostenfrei: Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/ncp.11253
 DOI: https://doi.org/10.1002/ncp.11253
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:autologous gut reconstruction
 intestinal failure
 parenteral nutrition
 quality of life
 short bowel syndrome
K10plus-PPN:1919712577
Verknüpfungen:→ Zeitschrift

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