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Verfasst von:Heer, Tobias [VerfasserIn]   i
 Zeymer, Uwe [VerfasserIn]   i
 Hochadel, Matthias [VerfasserIn]   i
 Frankenstein, Lutz [VerfasserIn]   i
 Pauschinger, Matthias [VerfasserIn]   i
 Hambrecht, Rainer [VerfasserIn]   i
 Bruder, Oliver Helge Willy [VerfasserIn]   i
 Böhm, Michael [VerfasserIn]   i
 Maier, Lars Siegfried [VerfasserIn]   i
 Zahn, Ralf [VerfasserIn]   i
 Senges, Jochen [VerfasserIn]   i
Titel:Influence of prior myocardial infarction on outcome in patients with ischaemic HFrEF
Titelzusatz:insights from the EVIdence based TreAtment in Heart Failure (EVITA-HF) registry
Verf.angabe:Tobias Heer, Uwe Zeymer, Matthias Hochadel, Lutz Frankenstein, Matthias Pauschinger, Rainer Hambrecht, Oliver Bruder, Michael Böhm, Lars S. Maier, Ralf Zahn, Jochen Senges
E-Jahr:2024
Jahr:8 May 2024
Umfang:12 S.
Illustrationen:Illustrationen
Fussnoten:Gesehen am 24.03.2025
Titel Quelle:Enthalten in: Clinical research in cardiology
Ort Quelle:Berlin : Springer, 2006
Jahr Quelle:2024
Band/Heft Quelle:(2024), ahead of print, Seite [1-12]
ISSN Quelle:1861-0692
Abstract:BACKGROUND: There is scarce information about the influence of prior myocardial infarction (pMI) on outcomes in patients (pts) with ischaemic HFrEF. We analysed data from the EVIdence based TreAtment in Heart Failure (EVITA-HF) registry. - METHODS: EVITA-HF comprises web-based case report data on demography, diagnostic measures, adverse events and 1-year follow-up of patients hospitalized for chronic heart failure ≥ 3 months (CHF) and an ejection fraction ≤ 40%. In the present study, we focused on the outcomes of pts with and without pMI in ischaemic HFrEF. - RESULTS: Between February 2009 and November 2015, a total of 2075 consecutive pts with ischaemic HFrEF were included from 16 centres in Germany. A total of 81.2% were male, and the mean age was 71 years. A total of 61.5% of the pts with ischaemic HFrEF had a history of pMI. These pts were treated less often with PCI (20.0 vs. 31.0%, p < 0.001) or CABG (3.8 vs. 7.7%, p < 0.001). They more often received an ICD (40.9 vs. 28.7%, p < 0.001), but less often a CRT-D (11.3 vs. 19.4%, p < 0.001). After multivariate adjustment, pts with pMI had a greater all-cause mortality after 1 year than those without pMI (hazard ratio 1.4; 95% CI, 1.10-1.79, p = 0.007). The combined endpoint of death, resuscitation or ICD shock after 1 year was greater in patients with pMI (20.8 vs. 16.4%, p = 0.03). Mobility was more often reduced in pts with pMI (46.8% vs. 40.1%, p = 0.03), and overall health status was more frequently worse in patients with pMI than in those 12 months ago (23.1 vs. 15.9%, p = 0.01). More than a quarter of the pts with ischaemic HFrEF were anxious or depressive. - CONCLUSION: pMI in patients with CHF and ischaemic HFrEF was associated with increased mortality, increased event rates, and worsened health status. Hence, the subgroup of pts with ischaemic HFrEF and pMI is at higher risk and deserves special attention.
DOI:doi:10.1007/s00392-024-02455-w
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

kostenfrei: Volltext: https://doi.org/10.1007/s00392-024-02455-w
 kostenfrei: Volltext: https://link.springer.com/article/10.1007/s00392-024-02455-w
 DOI: https://doi.org/10.1007/s00392-024-02455-w
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:Health status
 Ischaemic HFrEF
 Outcome
 Prior myocardial infarction
K10plus-PPN:1920415882
Verknüpfungen:→ Zeitschrift

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