Factors influencing background parenchymal enhancement in contrast-enhanced mammography images

• Verfasst von: Wessling, Daniel [VerfasserIn]
• Verfasst von: Männlin, Simon Johannes [VerfasserIn]
• Verfasst von: Schwarz, Ricarda [VerfasserIn]
• Verfasst von: Hagen, Florian [VerfasserIn]
• Verfasst von: Brendlin, Andreas Stefan [VerfasserIn]
• Verfasst von: Gassenmaier, Sebastian [VerfasserIn]
• Verfasst von: Preibsch, Heike [VerfasserIn]
• Titel: Factors influencing background parenchymal enhancement in contrast-enhanced mammography images
• Verf.angabe: Daniel Wessling, Simon Männlin, Ricarda Schwarz, Florian Hagen, Andreas Brendlin, Sebastian Gassenmaier and Heike Preibsch
• E-Jahr: 2024
• Jahr: 8 October 2024
• Umfang: 11 S.
• Fussnoten: Gesehen am 31.03.2025
• Weitere Titel: Titel des special issue: Diagnosis and Precision in Breast Cancer
• Titel Quelle: Enthalten in: Diagnostics
• Ort Quelle: Basel : MDPI, 2011
• Jahr Quelle: 2024
• Band/Heft Quelle: 14(2024), 19, special issue, Artikel-ID 2239, Seite 1-11
• ISSN Quelle: 2075-4418
• DOI: doi:10.3390/diagnostics14192239
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: breast density
• Sach-SW: female
• Sach-SW: mammography
• K10plus-PPN: 1920869735

Abstract

Background: The aim of this study is to evaluate the correlation between background parenchymal enhancement (BPE) and various patient-related and technical factors in recombined contrast-enhanced spectral mammography (CESM) images. Material and Methods: We assessed CESM images from 62 female patients who underwent CESM between May 2017 and October 2019, focusing on factors influencing BPE. A total of 235 images, all acquired using the same mammography machine, were analyzed. A region of interest (ROI) with a standard size of 0.75 to 1 cm2 was used to evaluate the minimal, maximal, and average pixel intensity enhancement. Additionally, the images were qualitatively assessed on a scale from 1 (minimal BPE) to 4 (marked BPE). We examined correlations with body mass index (BMI), age, hematocrit, hemoglobin levels, cardiovascular conditions, and the amount of pressure applied during the examination. Results: Our study identified a significant correlation between the amount of pressure applied during the examination and the BPE (Spearman’s ρ = 0.546). Additionally, a significant but weak correlation was observed between BPE and BMI (Spearman’s ρ = 0.421). No significant associations were found between BPE and menopausal status, cardiovascular preconditions, hematocrit, hemoglobin levels, breast density, or age. Conclusions: Patient-related and procedural factors significantly influence BPE in CESM images. Specifically, increased applied pressure and BMI are associated with higher BPE.