Hypoxia and Tumor Microenvironment

• Titel: Hypoxia and Tumor Microenvironment
• Titelzusatz: Implications for Cancer Therapy
• Mitwirkende: Mukherjee, Sukhes [HerausgeberIn]
• Mitwirkende: Kanwar, Jagat Rakesh [HerausgeberIn]
• Verf.angabe: edited by Sukhes Mukherjee, Jagat Rakesh Kanwar
• Ausgabe: 1st ed. 2025.
• Verlagsort: Singapore
• Verlagsort: Singapore
• Verlag: Springer Nature Singapore
• Verlag: Imprint: Springer
• E-Jahr: 2025
• Jahr: 2025.
• Jahr: 2025.
• Umfang: 1 Online-Ressource(XIV, 236 p. 45 illus. in color.)
• ISBN: 978-981-9610-16-7
• DOI: doi:10.1007/978-981-96-1016-7
• Datenträger: Online-Ressource
• Sprache: eng
• Bibliogr. Hinweis: Erscheint auch als : Druck-Ausgabe
• Bibliogr. Hinweis: Erscheint auch als : Druck-Ausgabe
• Bibliogr. Hinweis: Erscheint auch als : Druck-Ausgabe
• K10plus-PPN: 1920925201
• K10plus-PPN:
  Universitätsbibliothek
• Lokale URL UB: Zum Volltext
• Lokale URL UB: Bibliothek der Medizinischen Fakultät Mannheim der Universität Heidelberg
• Bibliothek/Idn: UW / m4695914670
• Lokale URL Inst.: Zum Volltext

Abstract

-- Chapter 1: Tumor Hypoxia An Introduction -- Chapter 2: Hypoxia and tumor immunity -- Chapter 3: Incipient Role of Non coding RNAs in different types of cancer hypoxia -- Chapter 4: Hypoxia induced DNA damage response and genomic instability dictate cancer treatment response -- Chapter 5: Metabolic regulation of CAR T cell function by hypoxic tumor -- Chapter 6: Emerging roles of non coding RNAs in tumor hypoxia -- Chapter 7: Regulation of Angiogenesis by Cancer Hypoxia and Role of Hypoxia Inducible Factors with Therapeutic Paradigm -- Chapter 8: Hypoxia and Regulation of Cancer Cell Stemness -- Chapter 9: Hypoxia-Inducible Factors: Regulation and Therapeutic Potential in Cancer: Artificial Intelligence in Precision Medicine -- Chapter 10: Strategic application of bio reductive metalloprodrugs for cancer cell-selective anticancer therapy -- Chapter 11: Hypoxia Inducible Factors Regulation and Therapeutic Potential.

Abstract

This book provides a comprehensive overview of the hypoxic tumor microenvironment and its impact on various aspects of cancer biology, including DNA damage response, genome instability, tumor immunity, non-coding RNA regulation, metabolic regulation of CAR-T cell function, and angiogenesis. It explores the regulation and therapeutic potential of hypoxia-inducible factors, as well as strategies to improve cancer immunotherapy by targeting the hypoxic tumor microenvironment. This book is a valuable resource for students, researchers, and Medical science professionals interested in understanding the complex interplay between hypoxia and cancer biology.