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Status: Bibliographieeintrag

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Verfasst von:Tan, Bingyao [VerfasserIn]   i
 Shah, Janika N. [VerfasserIn]   i
 McNabb, Ryan P. [VerfasserIn]   i
 Jayaraman, Swathi [VerfasserIn]   i
 Wong, Damon [VerfasserIn]   i
 Chua, Jacqueline [VerfasserIn]   i
 Ang, Marcus [VerfasserIn]   i
 Saw, Seang Mei [VerfasserIn]   i
 Jonas, Jost B. [VerfasserIn]   i
 Kuo, Anthony N. [VerfasserIn]   i
 Hoang, Quan V. [VerfasserIn]   i
 Schmetterer, Leopold [VerfasserIn]   i
Titel:Distortion-corrected posterior ocular shape in myopic eyes assessed by ultrawide OCT detects deformations associated With vision-threatening changes
Verf.angabe:Bingyao Tan, Janika N. Shah, Ryan P. McNabb, Swathi Jayaraman, Damon Wong, Jacqueline Chua, Marcus Ang, Seang Mei Saw, Jost B. Jonas, Anthony N. Kuo, Quan V. Hoang and Leopold Schmetterer
E-Jahr:2024
Jahr:November 2024
Umfang:9 S.
Illustrationen:Illustrationen
Fussnoten:Gesehen am 15.05.2025
Titel Quelle:Enthalten in: Investigative ophthalmology & visual science
Ort Quelle:Rockville, Md. : ARVO, 1977
Jahr Quelle:2024
Band/Heft Quelle:65(2024), 13, Artikel-ID 22, Seite 1-9
ISSN Quelle:1552-5783
Abstract:To develop a quantitative tool for assessing the posterior ocular shape using widefield, volumetric optical coherence tomography (OCT) in eyes with myopia. This observational, cross-sectional study included 178 eyes from 113 participants. Participants underwent a standardized eye examination, including ocular biometry and a custom ultrawide OCT. True ocular shape was reconstructed by tracing the beam propagation from the system to the posterior eye. Gaussian curvature quantified the localized ocular shape, which was further categorized into five distinct categories. An ocular shape irregularity (OSI) was calculated using principal component analysis. Linear regression with breakpoints analyzed the relationship between ocular shape parameters and axial length (AL). Increased curvature mean and variance were associated with more severe myopia (P < 0.001). Curvature categories (convex, normal, concave, and highly concave) differed significantly between the groups (all P < 0.001). Their correlations with AL revealed significant breakpoints between 27.1 and 27.2 mm. OSI, as a single metric for quantifying ocular shape distortion, was associated with more severe myopia (P < 0.001), and its correlation with AL revealed a breakpoint at 27.2 mm with a fourfold increase in slope steepness beyond this pivot. Determination of OSI was highly reproducible and could also be obtained with fewer scans. Eyes exceeding 27.2 mm in length exhibit pronounced shape changes. Our framework can be seamlessly integrated into commercial OCTs for ocular shape deformation detection, which could aid in identifying eyes with pathologic myopia.
DOI:doi:10.1167/iovs.65.13.22
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

kostenfrei: Volltext: https://doi.org/10.1167/iovs.65.13.22
 kostenfrei: Volltext: https://iovs.arvojournals.org/article.aspx?articleid=2802226
 DOI: https://doi.org/10.1167/iovs.65.13.22
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:192573045X
Verknüpfungen:→ Zeitschrift

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