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Verfasst von:Knops, Reinoud E. [VerfasserIn]   i
 de Veld, Jolien A. [VerfasserIn]   i
 Ghani, Abdul [VerfasserIn]   i
 Boersma, Lucas V.A. [VerfasserIn]   i
 Kuschyk, Jürgen [VerfasserIn]   i
 El Chami, Mikhael F. [VerfasserIn]   i
 Bonnemeier, Hendrik [VerfasserIn]   i
 Behr, Elijah R. [VerfasserIn]   i
 Brouwer, Tom F. [VerfasserIn]   i
 Kääb, Stefan [VerfasserIn]   i
 Mittal, Suneet [VerfasserIn]   i
 Pepplinkhuizen, Shari [VerfasserIn]   i
 Quast, Anne-Floor B.E. [VerfasserIn]   i
 Smeding, Lonneke [VerfasserIn]   i
 van der Stuijt, Willeke [VerfasserIn]   i
 de Weger, Anouk [VerfasserIn]   i
 Bijsterveld, Nick R. [VerfasserIn]   i
 Richter, Sergio [VerfasserIn]   i
 Brouwer, Marc A. [VerfasserIn]   i
 de Groot, Joris R. [VerfasserIn]   i
 Kooiman, Kirsten M. [VerfasserIn]   i
 Lambiase, Pier D. [VerfasserIn]   i
 Neuzil, Petr [VerfasserIn]   i
 Vernooy, Kevin [VerfasserIn]   i
 Alings, Marco [VerfasserIn]   i
 Betts, Timothy R. [VerfasserIn]   i
 Bracke, Frank A.L.E. [VerfasserIn]   i
 Burke, Martin C. [VerfasserIn]   i
 de Jong, Jonas S.S.G. [VerfasserIn]   i
 Wright, David J. [VerfasserIn]   i
 Jansen, Ward P.J. [VerfasserIn]   i
 Whinnett, Zachary I. [VerfasserIn]   i
 Nordbeck, Peter [VerfasserIn]   i
 Knaut, Michael [VerfasserIn]   i
 Philbert, Berit T. [VerfasserIn]   i
 van Opstal, Jurren M. [VerfasserIn]   i
 Chicos, Alexandru B. [VerfasserIn]   i
 Allaart, Cornelis P. [VerfasserIn]   i
 Borger van der Burg, Alida E. [VerfasserIn]   i
 Dizon, Jose M. [VerfasserIn]   i
 Miller, Marc A. [VerfasserIn]   i
 Nemirovksy, Dmitry [VerfasserIn]   i
 Surber, Ralf [VerfasserIn]   i
 Upadhyay, Gaurav A. [VerfasserIn]   i
 Tijssen, Jan G.P. [VerfasserIn]   i
 Wilde, Arthur A.M. [VerfasserIn]   i
 Olde Nordkamp, Louise R.A. [VerfasserIn]   i
Titel:Quality of Life in Subcutaneous or Transvenous Implantable Cardioverter-Defibrillator Patients
Titelzusatz:A Secondary Analysis of the PRAETORIAN Trial
Verf.angabe:Reinoud E. Knops , MD, PhD; Jolien A. de Veld , MD; Abdul Ghani, MD, PhD; Lucas V.A. Boersma , MD, PhD; Juergen Kuschyk , MD; Mikhael F. El Chami , MD; Hendrik Bonnemeier , MD, PhD; Elijah R. Behr , MD; Tom F. Brouwer , MD, PhD; Stefan Kääb , MD, PhD; Suneet Mittal , MD; Shari Pepplinkhuizen , MD; Anne-Floor B.E. Quast , MD, PhD; Lonneke Smeding , PhD; Willeke van der Stuijt , MD, PhD; Anouk de Weger , MSc; Nick R. Bijsterveld , MD, PhD; Sergio Richter , MD; Marc A. Brouwer, MD, PhD; Joris R. de Groot , MD, PhD; Kirsten M. Kooiman , MPA; Pier D. Lambiase , MD, PhD; Petr Neuzil , MD, PhD; Kevin Vernooy , MD, PhD; Marco Alings , MD, PhD; Timothy R. Betts , MD; Frank A.L.E. Bracke , MD, PhD; Martin C. Burke , DO; Jonas S.S.G. de Jong , MD, PhD; David J. Wright , MD; Ward P.J. Jansen , MD, PhD; Zachary I. Whinnett , MD, PhD; Peter Nordbeck , MD; Michael Knaut , MD; Berit T. Philbert , MD; Jurren M. van Opstal , MD, PhD; Alexandru B. Chicos , MD; Cornelis P. Allaart , MD, PhD; Alida E. Borger van der Burg , MD, PhD; Jose M. Dizon , MD; Marc A. Miller, MD; Dmitry Nemirovksy, MD; Ralf Surber , MD; Gaurav A. Upadhyay , MD; Jan G.P. Tijssen , MD, PhD; Arthur A.M. Wilde , MD, PhD; Louise R.A. Olde Nordkamp , MD, PhD; on behalf of the PRAETORIAN Investigators
E-Jahr:2024
Jahr:Nov 2024
Umfang:10 S.
Illustrationen:Illustrationen
Fussnoten:Online veröffentlicht: 19. November 2024 ; Gesehen am 20.05.2025
Titel Quelle:Enthalten in: Circulation. Cardiovascular quality and outcomes
Ort Quelle:Philadelphia, Pa. : Lippincott, Williams & Wilkins, 2008
Jahr Quelle:2024
Band/Heft Quelle:17(2024), 11, Artikel-ID e010822, Seite 1156-1165
ISSN Quelle:1941-7705
Abstract:BACKGROUND: - The subcutaneous implantable cardioverter-defibrillator (S-ICD) was developed to overcome the risk of lead-related complications associated with the transvenous implantable cardioverter-defibrillator (TV-ICD). In contrast to the TV-ICD, the S-ICD is a completely extrathoracic device. Subsequently, complications differ between these 2 implantable cardioverter-defibrillators, which might impact patient perceptions of the therapies. This prespecified secondary analysis of the PRAETORIAN trial evaluates differences in quality of life. - METHODS: - The PRAETORIAN trial (A Prospective, Randomized Comparison of Subcutaneous and Transvenous Implantable Cardioverter Defibrillator Therapy) randomized patients with an implantable cardioverter-defibrillator indication, without the need for pacing to S-ICD or TV-ICD therapy. Two questionnaires were collected at baseline, discharge, 12 months, and 30 months. The Duke Activity Status Index measures cardiac-specific physical functioning, and the 36-Item Short Form Health Survey measures physical and mental well-being, with the subscales bodily pain and mental health being of interest in this analysis. Mann-Whitney U tests were used to compare study arms, and a mixed model was used to describe the questionnaire outcomes over time. - RESULTS: - Patients were randomized to S-ICD (n=426) and TV-ICD (n=423). In the S-ICD group, 20% were women versus 19% in the TV-ICD group. The median age was 63 (interquartile range, 54-69) years in the S-ICD group versus 64 (interquartile range, 56-69) years in the TV-ICD group. There were no significant differences in the Duke Activity Status Index and 36-Item Short Form Health Survey subscales for bodily pain and mental health between the groups at any time point. Patients with a shock in the last 90 days had significantly lower scores for social functioning (P=0.008) and role limitations due to emotional problems (P=0.001) than patients without a shock, but this effect did not differ between treatment arms. - CONCLUSIONS: - In a large randomized cohort of patients with an S-ICD or TV-ICD, no difference in overall quality of life was observed. However, implantable cardioverter-defibrillator shocks resulted in a reduction in quality of life, regardless of the device type or appropriateness. - REGISTRATION: - URL: https://www.clinicaltrials.gov; Unique identifier: NCT01296022.
DOI:doi:10.1161/CIRCOUTCOMES.124.010822
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

kostenfrei: Volltext: https://doi.org/10.1161/CIRCOUTCOMES.124.010822
 kostenfrei: Volltext: https://www.ahajournals.org/doi/10.1161/CIRCOUTCOMES.124.010822
 DOI: https://doi.org/10.1161/CIRCOUTCOMES.124.010822
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:1926128745
Verknüpfungen:→ Zeitschrift

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