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| Verfasst von: | Ammann, Yanic Rolf [VerfasserIn]  |
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| | Klein, Marie [VerfasserIn] |
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| | Marti, Lukas [VerfasserIn] |
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| | Warschkow, Rene [VerfasserIn] |
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| | Ströse, Lennard [VerfasserIn] |
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| | Sparn, Moritz [VerfasserIn] |
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| | Jäger, Tarkan [VerfasserIn] |
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| | Bischofberger, Stephan [VerfasserIn] |
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| | Brunner, Walter [VerfasserIn] |
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| Titel: | Does transanal total mesorectal excision (taTME) result in better quality of life and functional outcomes than traditional TME does? |
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| Titelzusatz: | a retrospective propensity score-adjusted cohort study : research |
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| Verf.angabe: | Yanic Ammann, Marie Klein, Lukas Marti, Rene Warschkow, Lennard Ströse, Moritz Sparn, Tarkan Jäger, Stephan Bischofberger, Walter Brunner |
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| E-Jahr: | 2025 |
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| Jahr: | December 2025 |
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| Umfang: | 12 S. |
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| Fussnoten: | Online veröffentlicht: 30. April 2025 ; Gesehen am 27.05.2025 |
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| Titel Quelle: | Enthalten in: Langenbeck's archives of surgery |
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| Ort Quelle: | Berlin : Springer, 1998 |
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| Jahr Quelle: | 2025 |
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| Band/Heft Quelle: | 410(2025), 1 vom: Dez., Artikel-ID 149, Seite 1-12 |
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| ISSN Quelle: | 1435-2451 |
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| Abstract: | Purpose The improved prognosis of rectal cancer through modern therapeutic approaches raises questions regarding quality of life (QoL) and functional outcomes. In this study, we compared post-transanal total mesorectal excision (taTME) short- and long-term QoL and functional outcomes with those after abdominal TME (abTME). Methods Prospective data from patients who underwent elective taTME or abTME for stage I-III rectal cancer followed by anastomosis were retrospectively propensity score-adjusted. The primary endpoint, QoL, was assessed with the European Organization for Research and Treatment of Cancer core questionnaire (EORTC QLQ-C30). Functional outcomes were the secondary endpoints. Results Among 494 patients during 2013-2022, 187 patients who underwent taTME and 62 patients who underwent abTME were included. QoL was worse after taTME at isolated time points: overall QoL (after 3 years: 72 vs. 82 points, p = 0.017) and QLQ-total (after 3 years: 81 vs. 87 points, p = 0.028; after 4 years: 82 vs. 89 points, p = 0.012). After propensity score matching, the between-group differences were still significant but smaller: overall QoL − 6 points, p = 0.021; QLQ-total − 5 points, p = 0.026. Conclusion The differences reported at isolated time points have questionable clinical relevance. Therefore, taTME and traditional abTME seem to have comparable long-term QoL and functional outcomes. Clinical trial registration ClinicalTrials.gov, NCT06505863, https://clinicaltrials.gov/search?id=NCT06505863 . |
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| DOI: | doi:10.1007/s00423-025-03724-6 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
kostenfrei: Volltext: https://doi.org/10.1007/s00423-025-03724-6 |
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| | kostenfrei: Volltext: http://link.springer.com/article/10.1007/s00423-025-03724-6 |
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| | DOI: https://doi.org/10.1007/s00423-025-03724-6 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| K10plus-PPN: | 1926692241 |
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| Verknüpfungen: | → Zeitschrift |
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Does transanal total mesorectal excision (taTME) result in better quality of life and functional outcomes than traditional TME does? / Ammann, Yanic Rolf [VerfasserIn]; December 2025 (Online-Ressource)
