| |  Online-Ressource |
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| Verfasst von: | Atanasova, Konstantina [VerfasserIn]  |
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| | Knödler, Laura-Louise [VerfasserIn] |
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| | Reindl, Wolfgang [VerfasserIn] |
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| | Ebert, Matthias [VerfasserIn] |
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| | Thomann, Anne K. [VerfasserIn] |
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| Titel: | Role of the gut microbiome in psychological symptoms associated with inflammatory bowel diseases |
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| Titelzusatz: | review |
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| Verf.angabe: | Konstantina Atanasova, Laura-Louise Knödler, Wolfgang Reindl, Matthias Philip Ebert, Anne Kerstin Thomann |
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| E-Jahr: | 2025 |
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| Jahr: | Dezember 2025 |
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| Umfang: | 15 S. |
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| Illustrationen: | Illustrationen, Diagramme |
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| Fussnoten: | Online veröffentlicht: 27. Januar 2025 ; Gesehen am 07.07.2025 |
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| Titel Quelle: | Enthalten in: Seminars in immunopathology |
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| Ort Quelle: | Berlin : Springer, 2007 |
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| Jahr Quelle: | 2025 |
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| Band/Heft Quelle: | 47(2025), 1 vom: Dez., Artikel-ID 12, Seite 1-15 |
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| ISSN Quelle: | 1863-2300 |
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| Abstract: | The brain-gut axis constitutes the basis for the bidirectional communication between the central nervous system and the gastrointestinal tract driven by neural, hormonal, metabolic, immunological, and microbial signals. Alterations in the gut microbiome composition as observed in inflammatory bowel diseases can modulate brain function and emerging empirical evidence has indicated that interactions among the brain-gut microbiome-axis seem to play a significant role in the pathogenesis of both inflammatory bowel diseases and psychiatric disorders and their comorbidity. Yet, the immunological and molecular mechanisms underlying the co-occurrence of inflammatory bowel diseases and psychological symptoms are still poorly understood. The aim of this narrative review is to highlight contemporary empirical findings supporting a pivotal role of the gut microbiome in the pathophysiology of highly prevalent neuropsychiatric symptoms in inflammatory bowel diseases such as fatigue, depression, and anxiety. Finally, we focus on microbiome modulation as potential treatment option for comorbid neuropsychiatric symptoms in immune-mediated diseases and especially in inflammatory bowel diseases. High-quality clinical trials are required to clarify how microbiome modulation through dietary interventions or probiotic, prebiotic or synbiotic treatment can be used clinically to improve mental health and thus quality of life of patients with inflammatory bowel diseases. |
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| DOI: | doi:10.1007/s00281-025-01036-x |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
kostenfrei: Volltext: https://doi.org/10.1007/s00281-025-01036-x |
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| | DOI: https://doi.org/10.1007/s00281-025-01036-x |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Anxiety |
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| | Behavioral Medicine |
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| | Brain-gut axis |
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| | Depression |
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| | Fatigue |
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| | Gut microbiome |
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| | Inflammatory bowel disease |
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| | Mental Disorder |
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| | Mental Health |
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| | Psychiatric Disorder |
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| | Psychiatry |
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| | Psychopharmacology |
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| K10plus-PPN: | 1929874588 |
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| Verknüpfungen: | → Zeitschrift |
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Role of the gut microbiome in psychological symptoms associated with inflammatory bowel diseases / Atanasova, Konstantina [VerfasserIn]; Dezember 2025 (Online-Ressource)
