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Verfasst von:Jones, Leia R. [VerfasserIn]   i
 Zwart, Maurice J. W. [VerfasserIn]   i
 de Graaf, Nine [VerfasserIn]   i
 Wei, Kongyuan [VerfasserIn]   i
 Qu, Liu [VerfasserIn]   i
 Jiabin, Jin [VerfasserIn]   i
 Ningzhen, Fu [VerfasserIn]   i
 Wang, Shin-E [VerfasserIn]   i
 Kim, Hongbeom [VerfasserIn]   i
 Kauffmann, Emanuele F. [VerfasserIn]   i
 de Wilde, Roeland F. [VerfasserIn]   i
 Molenaar, I. Quintus [VerfasserIn]   i
 Chao, Ying Jui [VerfasserIn]   i
 Moraldi, Luca [VerfasserIn]   i
 Saint-Marc, Olivier [VerfasserIn]   i
 Nickel, Felix [VerfasserIn]   i
 Peng, Cheng-Ming [VerfasserIn]   i
 Kang, Chang Moo [VerfasserIn]   i
 Machado, Marcel [VerfasserIn]   i
 Luyer, Misha D. P. [VerfasserIn]   i
 Lips, Daan J. [VerfasserIn]   i
 Bonsing, Bert A. [VerfasserIn]   i
 Hackert, Thilo [VerfasserIn]   i
 Shan, Yan-Shen [VerfasserIn]   i
 Groot Koerkamp, Bas [VerfasserIn]   i
 Shyr, Yi-Ming [VerfasserIn]   i
 Shen, Baiyong [VerfasserIn]   i
 Boggi, Ugo [VerfasserIn]   i
 Liu, Rong [VerfasserIn]   i
 Jang, Jin-Young [VerfasserIn]   i
 Besselink, Marc G. [VerfasserIn]   i
 Abu Hilal, Mohammad [VerfasserIn]   i
Titel:Learning curve stratified outcomes after robotic pancreatoduodenectomy
Titelzusatz:international multicenter experience
Verf.angabe:Leia R. Jones, BSc, Maurice J.W. Zwart, PhD, MD, Nine de Graaf, MD, Kongyuan Wei, MD, Liu Qu, PhD, MD, Jin Jiabin, PhD, MD, Fu Ningzhen, MD, Shin-E Wang, PhD, MD, Hongbeom Kim, MD, Emanuele F. Kauffmann, PhD, MD, Roeland F. de Wilde, PhD, MD, I. Quintus Molenaar, PhD, MD, Ying Jui Chao, PhD, MD, Luca Moraldi, PhD, MD, Olivier Saint-Marc, MD, Felix Nickel, PhD, MD, Cheng-Ming Peng, PhD, MD, Chang Moo Kang, PhD, MD, Marcel Machado, PhD, MD, Misha D.P. Luyer, PhD, MD, Daan J. Lips, PhD, MD, Bert A. Bonsing, PhD, MD, Thilo Hackert, PhD, MD, Yan-Shen Shan, PhD, MD, Bas Groot Koerkamp, PhD, MD, Yi-Ming Shyr, PhD, MD, Baiyong Shen, PhD, MD, Ugo Boggi, MD, Rong Liu, PhD, MD, Jin-Young Jang, PhD, MD, Marc G. Besselink, PhD, MD, Mohammad Abu Hilal, PhD, MD, for the International Consortium on Minimally Invasive Pancreatic Surgery (I-MIPS)
E-Jahr:2024
Jahr:December 2024
Umfang:9 S.
Illustrationen:Illustrationen
Fussnoten:Online verfügbar 19 August 2024, Version des Artikels 12 November 2024 ; Gesehen am 10.07.2025
Titel Quelle:Enthalten in: Surgery
Ort Quelle:Amsterdam [u.a.] : Elsevier, 1995
Jahr Quelle:2024
Band/Heft Quelle:176(2024), 6 vom: Dez., Seite 1721-1729
ISSN Quelle:1532-7361
Abstract:Background - Robotic pancreatoduodenectomy is increasingly being implemented worldwide, with good results reported from individual expert centers. However, it is unclear to what extent outcomes will continue to improve during the learning curve, as large international studies are lacking. - Methods - An international retrospective multicenter case series, including consecutive patients after robotic pancreatoduodenectomy from 18 centers in 8 countries in Europe, Asia, and South America until December 31, 2019, was conducted. A cumulative sum analysis was performed to determine the inflection points for the feasibility (operative time and blood loss) and proficiency (postoperative pancreatic fistula grade B/C and major morbidity) learning curves. Outcomes were compared in 3 groups on the basis of the learning curve inflection points. - Results - Overall, 2,186 patients after robotic pancreatoduodenectomy were included. The feasibility learning curve was reached after 30-45 robotic pancreatoduodenectomy procedures and the proficiency learning curve after 90 robotic pancreatoduodenectomy procedures. These inflection points created 3 phases, which were associated with major morbidity (24.7%, 23.4%, and 12.3%, P < .001) but not 30-day mortality (2.1%, 2.0%, and 1.5%, P = .670). Other outcomes mostly continued to improve, including median operative time 432, 390, and 300 minutes (P < .0001), conversion 6.0%, 4.7%, and 2.7% (P = .002), bile leakage 7.2%, 4.1%, and 2.4% (P < .001), postpancreatectomy hemorrhage 6.5%, 6.1%, and 1.8% (n = 21) but not R0 resection (pancreatic ductal adenocarcinoma only) 78.5%, 73.9%, and 82.8% (P = .35), and 90-day mortality rate 3.1%, 3.5%, and 2.1% (P = .191). Centers performing >20 robotic pancreatoduodenectomies annually had lower rates of conversion, reoperation, and shorter median operative time as compared with centers performing 10-20 robotic pancreatoduodenectomies annually. - Conclusion - This international multicenter study demonstrates that most outcomes of robotic pancreatoduodenectomy continued to improve during 3 learning curve phases without a negative effect on 90-day mortality. Randomized studies are needed in high-volume centers that have surpassed the first learning curves, to compare these outcomes with the open approach.
DOI:doi:10.1016/j.surg.2024.05.044
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

kostenfrei: Volltext: https://doi.org/10.1016/j.surg.2024.05.044
 kostenfrei: Volltext: https://www.sciencedirect.com/science/article/pii/S0039606024003751
 DOI: https://doi.org/10.1016/j.surg.2024.05.044
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:1930200951
Verknüpfungen:→ Zeitschrift

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