Predictive value of renal shear wave elastography in liver cirrhosis

• Verfasst von: Hagel, Christian [VerfasserIn]
• Verfasst von: Hirth, Michael [VerfasserIn]
• Verfasst von: Bißbort, Jan [VerfasserIn]
• Verfasst von: Teufel, Andreas [VerfasserIn]
• Verfasst von: Hetjens, Svetlana [VerfasserIn]
• Verfasst von: Ebert, Matthias [VerfasserIn]
• Verfasst von: Antoni, Christoph Helmer [VerfasserIn]
• Titel: Predictive value of renal shear wave elastography in liver cirrhosis
• Titelzusatz: liver, pancreas and biliary tract
• Verf.angabe: Christian Hagel, Michael Hirth, Jan Bißbort, Andreas Teufel, Svetlana Hetjens, Matthias P. Ebert, Christoph Antoni
• E-Jahr: 2025
• Jahr: February 2025
• Umfang: 7 S.
• Illustrationen: Diagramme
• Fussnoten: Online verfügbar: 28. Oktober 2024, Artikelversion: 24. Januar 2025 ; Gesehen am 10.07.2025
• Titel Quelle: Enthalten in: Digestive and liver disease
• Ort Quelle: [Erscheinungsort nicht ermittelbar] : Saunders, 2000
• Jahr Quelle: 2025
• Band/Heft Quelle: 57(2025), 2 vom: Feb., Seite 512-518
• ISSN Quelle: 1878-3562
• DOI: doi:10.1016/j.dld.2024.10.018
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: Acoustic radiation force impulse imaging
• Sach-SW: Heparorenale syndrome
• Sach-SW: Liver cirrhosis
• Sach-SW: Shear wave elastography
• K10plus-PPN: 1930260385

Abstract

Background - In liver cirrhosis, prognosis is profoundly affected by renal function. This study evaluates the usefulness of renal stiffness measurement by point-shear wave elastography and renal perfusion by duplex. - Methods - In this case-control study, organ stiffness was quantified using point-shear wave elastography and duplex sonography to calculate the arterial resistive (RI) and pulsatility indices (PI) in 123 patients, including patients with liver cirrhosis with (LC+A) and without ascites (LC-A) and patients without liver cirrhosis (NLC). - Results - PI and RI were significantly increased in LC-A and LC+A compared to NLC (p<0.001) and correlated with MELD and Child Pugh scores. Point-shear wave elastography showed significantly lower renal stiffness in LC+A compared to LC-A (p<0.01) and NLC (p<0.001). Renal stiffness correlated inversely with MELD and Child Pugh scores. Reduced renal stiffness, but not PI or RI, was associated with the presence of hepatorenal syndrome (p<0.001). Reduced renal stiffness was associated with an increased risk of death due to complications of liver cirrhosis within 3 years (p<0.01). - Conclusion - Point-shear wave elastography and duplex sonography correlate with progression of liver cirrhosis, but only shear wave elastography represents a valuable prognostic tool for hepatorenal syndrome and mortality in patients with liver cirrhosis.