| Online-Ressource |
Verfasst von: | Hastings, Margaret H. [VerfasserIn]  |
| Castro, Claire [VerfasserIn]  |
| Freeman, Rebecca [VerfasserIn]  |
| Abdul Kadir, Azrul [VerfasserIn]  |
| Lerchenmüller, Carolin [VerfasserIn]  |
| Li, Haobo [VerfasserIn]  |
| Rhee, James [VerfasserIn]  |
| Roh, Jason D. [VerfasserIn]  |
| Roh, Kangsan [VerfasserIn]  |
| Singh, Anand P. [VerfasserIn]  |
| Wu, Chao [VerfasserIn]  |
| Xia, Peng [VerfasserIn]  |
| Zhou, Qiulian [VerfasserIn]  |
| Xiao, Junjie [VerfasserIn]  |
| Rosenzweig, Anthony [VerfasserIn]  |
Titel: | Intrinsic and extrinsic contributors to the cardiac benefits of exercise |
Verf.angabe: | Margaret H. Hastings, PHD, Claire Castro, PHD, Rebecca Freeman, BA, Azrul Abdul Kadir, PHD, Carolin Lerchenmüller, MD, Haobo Li, PHD,James Rhee, MD, PHD, Jason D. Roh, MD, MHS, Kangsan Roh, PHD, Anand P. Singh, PHD, Chao Wu, MD, PHD, Peng Xia, PHD, Qiulian Zhou, PHD, Junjie Xiao, MD, PHD, Anthony Rosenzweig, MD |
E-Jahr: | 2024 |
Jahr: | April 2024 |
Umfang: | 18 S. |
Illustrationen: | Illustrationen |
Fussnoten: | Online verfügbar: 18. Oktober 2023, Artikelversion: 22. April 2024 ; Gesehen am 16.07.2025 |
Titel Quelle: | Enthalten in: JACC Basic to translational science |
Ort Quelle: | Washington, DC : American College of Cardiology, 2016 |
Jahr Quelle: | 2024 |
Band/Heft Quelle: | 9(2024), 4 vom: Apr., Seite 535-552 |
ISSN Quelle: | 2452-302X |
Abstract: | Among its many cardiovascular benefits, exercise training improves heart function and protects the heart against age-related decline, pathological stress, and injury. Here, we focus on cardiac benefits with an emphasis on more recent updates to our understanding. While the cardiomyocyte continues to play a central role as both a target and effector of exercise’s benefits, there is a growing recognition of the important roles of other, noncardiomyocyte lineages and pathways, including some that lie outside the heart itself. We review what is known about mediators of exercise’s benefits—both those intrinsic to the heart (at the level of cardiomyocytes, fibroblasts, or vascular cells) and those that are systemic (including metabolism, inflammation, the microbiome, and aging)—highlighting what is known about the molecular mechanisms responsible. |
DOI: | doi:10.1016/j.jacbts.2023.07.011 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
kostenfrei: Volltext: https://doi.org/10.1016/j.jacbts.2023.07.011 |
| kostenfrei: Volltext: https://www.sciencedirect.com/science/article/pii/S2452302X23002942 |
| DOI: https://doi.org/10.1016/j.jacbts.2023.07.011 |
Datenträger: | Online-Ressource |
Sprache: | eng |
Sach-SW: | coronary microvasculature |
| fibrosis |
| inflammation |
| microbiome |
| physiological cardiac hypertrophy |
K10plus-PPN: | 1930711026 |
Verknüpfungen: | → Zeitschrift |
Intrinsic and extrinsic contributors to the cardiac benefits of exercise / Hastings, Margaret H. [VerfasserIn]; April 2024 (Online-Ressource)