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Verfasst von:Lunz, André [VerfasserIn]   i
 Geisbüsch, Andreas [VerfasserIn]   i
 Omlor, Georg [VerfasserIn]   i
 Horsch, Axel [VerfasserIn]   i
 Renkawitz, Tobias [VerfasserIn]   i
 Lehner, Burkhard [VerfasserIn]   i
Titel:Differences in success rate of two-stage revision for periprosthetic joint infection of the knee depending on the applied definition
Verf.angabe:Andre Lunz, Andreas Geisbüsch, Georg W. Omlor, Axel Horsch, Tobias Renkawitz, Burkhard Lehner
E-Jahr:2025
Jahr:March 2025
Umfang:7 S.
Illustrationen:Illustrationen
Fussnoten:Online verfügbar: 14 September 2024 ; Gesehen am 16.07.2025
Titel Quelle:Enthalten in: The journal of arthroplasty
Ort Quelle:Orlando, Fla. : Churchill Livingstone, 1986
Jahr Quelle:2025
Band/Heft Quelle:40(2025), 3, Seite 758-764
ISSN Quelle:1532-8406
Abstract:BACKGROUND: Success rates of two-stage exchange arthroplasty are subject to substantial variance in the literature. An explanation is the lack of a universally accepted definition of what constitutes treatment success for periprosthetic joint infection. Therefore, the main objective of this study was to assess success rates, applying four definitions to identify the one definition that best captures "true" success from both a clinical and patient-centered perspective. - METHODS: This was a retrospective study investigating the outcome of a consecutive series of 78 chronic knee periprosthetic joint infections that were treated with a two-stage revision at a single center between 2017 and 2020. Kaplan-Meier survival analyses were conducted to estimate success rates. - RESULTS: After a mean follow-up of 36 months (range, 25 to 60), 64 patients (82%) were reimplanted after a mean interim period of 90 days (range, 22 to 201). There was one patient (1%) lost to follow-up, and the overall mortality was 15% (n = 12). Kaplan-Meier survival analyses were used to estimate treatment success at two and three years: implant survival was 93% (95% confidence interval [CI]: 82 to 97) and 87% (95% CI: 73 to 94), infection control was 90% (95% CI: 79 to 95) and 87% (95% CI: 73 to 93), success according to Delphi criteria was 88% (95% CI: 78 to 94), and success according to Musculoskeletal Infection Society criteria was 65% (95% CI: 53 to 74) at both timepoints. - CONCLUSIONS: Success rates were ranging between 65 and 93% depending on the applied definition, highlighting the need for universal success criteria. This variability mainly results from the differing approaches to patients who did not undergo reimplantation or passed away within a year of surgery. These patients exemplify cases of fatal treatment failures. Consequently, the Musculoskeletal Infection Society criteria should be routinely employed to accurately report the "true" success rate.
DOI:doi:10.1016/j.arth.2024.09.007
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.1016/j.arth.2024.09.007
 Volltext: https://www.sciencedirect.com/science/article/pii/S0883540324009458
 DOI: https://doi.org/10.1016/j.arth.2024.09.007
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:Adult
 Aged
 Aged, 80 and over
 Arthroplasty, Replacement, Knee
 Delphi criteria
 Female
 Humans
 infection control
 Kaplan-Meier Estimate
 Knee Joint
 Knee Prosthesis
 Male
 Middle Aged
 MSIS criteria
 periprosthetic joint infection
 Prosthesis-Related Infections
 Reoperation
 Retrospective Studies
 Treatment Outcome
 treatment success
 two-stage exchange arthroplasty
K10plus-PPN:1930902271
Verknüpfungen:→ Zeitschrift

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