The expression of a hunchback ortholog in the polychaete annelid Platynereis dumerilii suggests an ancestral role in mesoderm development and neurogenesis

• Verfasst von: Kerner, Pierre [VerfasserIn]
• Verfasst von: Arendt, Detlev [VerfasserIn]
• Titel: The expression of a hunchback ortholog in the polychaete annelid Platynereis dumerilii suggests an ancestral role in mesoderm development and neurogenesis
• Verf.angabe: Pierre Kerner, Fabiola Zelada González, Martine Le Gouar, Valérie Ledent, Detlev Arendt, Michel Vervoort
• Umfang: 8 S.
• Fussnoten: Gesehen am 17.05.2017
• Titel Quelle: Enthalten in: Development genes and evolution
• Jahr Quelle: 2006
• Band/Heft Quelle: 216(2006), 12, S. 821-828
• ISSN Quelle: 0949-944X
• DOI: doi:10.1007/s00427-006-0100-9
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1558727760

Abstract

Orthologs of the Drosophila gap gene hunchback have been isolated so far only in protostomes. Phylogenetic analysis of recently available genomic data allowed us to confirm that hunchback genes are widely found in protostomes (both lophotrochozoans and ecdysozoans). In contrast, no unequivocal hunchback gene can be found in the genomes of deuterostomes and non-bilaterians. We cloned hunchback in the marine polychaete annelid Platynereis dumerilii and analysed its expression during development. In this species, hunchback displays an expression pattern indicative of a role in mesoderm formation and neurogenesis, and similar to the expression found for hunchback genes in arthropods. These data suggest altogether that these functions are ancestral to protostomes.