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Status: Bibliographieeintrag

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Verfasst von:Upadhyay, Jaymin [VerfasserIn]   i
 Baumgärtner, Ulf [VerfasserIn]   i
 Treede, Rolf-Detlef [VerfasserIn]   i
Titel:Detection of central circuits implicated in the formation of novel pain memories
Verf.angabe:Jaymin Upadhyay, Julia Granitzka, Thomas Bauermann, Ulf Baumgärtner, Markus Breimhorst, Rolf-Detlef Treede, Frank Birklein
E-Jahr:2016
Jahr:15 September 2016
Umfang:11 S.
Fussnoten:Gesehen am 29.05.2020
Titel Quelle:Enthalten in: Journal of pain research
Ort Quelle:Albany, Auckland : Dove Medical Press, 2008
Jahr Quelle:2016
Band/Heft Quelle:9(2016), Seite 671-681
ISSN Quelle:1178-7090
Abstract:Detection of central circuits implicated in the formation of novel pain memories Jaymin Upadhyay,1 Julia Granitzka,1 Thomas Bauermann,2 Ulf Baumgärtner,3 Markus Breimhorst,1 Rolf-Detlef Treede,3 Frank Birklein1 1Department of Neurology, 2Department of Neuroradiology, University Medical Centre, Johannes Gutenberg University Mainz, Mainz, 3Department of Neurophysiology, Center for Biomedicine and Medical Technology Mannheim (CBTM), Heidelberg University, Mannheim, Germany Abstract: Being able to remember physically and emotionally painful events in one’s own past may shape behavior, and can create an aversion to a variety of situations. Pain imagination is a related process that may include recall of past experiences, in addition to production of sensory and emotional percepts without external stimuli. This study aimed to understand 1) the central nervous system processes that underlie pain imagination, 2) the retrieval of pain memories, and 3) to compare the latter with visual object memory. These goals were achieved by longitudinally investigating brain function with functional magnetic resonance imaging in a unique group of healthy volunteers who had never experienced tooth pain. In these subjects, we compared brain responses elicited during three experimental conditions in the following order: imagination of tooth pain (pain imagination), remembering one’s own house (object memory), and remembrance of tooth pain following an episode of induced acute tooth pain (pain memory). Key observations stemming from group-level conjunction analyses revealed common activation in the posterior parietal cortex for both pain imagination and pain memory, while object and pain memory each had strong activation predominantly within the middle frontal gyrus. When contrasting pain imagination and memory, significant activation differences were observed in subcortical structures (ie, parahippocampus – pain imagination > pain memory; midbrain – pain memory > pain imagination). Importantly, these findings were observed in the presence of consistent and reproducible psychophysical and behavioral measures that informed on the subjects’ ability to imagine novel and familiar thoughts, as well as the subjects’ pain perception. Keywords: fMRI, pain memory, pain imagination, object memory, tooth pain
DOI:doi:10.2147/JPR.S113436
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.2147/JPR.S113436
 Volltext: https://www.dovepress.com/detection-of-central-circuits-implicated-in-the-formation-of-novel-pai-peer-reviewed-article-J ...
 DOI: https://doi.org/10.2147/JPR.S113436
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:1587892936
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