The role of stem cell transplantation in the management of relapsed follicular lymphoma in the era of targeted therapies

• Verfasst von: Norman, Jane [VerfasserIn]
• Verfasst von: Dreger, Peter [VerfasserIn]
• Titel: The role of stem cell transplantation in the management of relapsed follicular lymphoma in the era of targeted therapies
• Verf.angabe: Jane E. Norman, Harry C. Schouten, Peter Dreger, Stephen P. Robinson
• Jahr: 2019
• Jahr des Originals: 2018
• Umfang: 11 S.
• Fussnoten: Published online: 2 November 2018 ; Gesehen am 19.09.2019
• Titel Quelle: Enthalten in: Bone marrow transplantation
• Ort Quelle: London : Springer Nature, 1997
• Jahr Quelle: 2019
• Band/Heft Quelle: 54(2019), 6, Seite 787-797
• ISSN Quelle: 1476-5365
• DOI: doi:10.1038/s41409-018-0372-5
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1677366648

Abstract

Patients with relapsed follicular lymphoma (FL) following first-line therapy have an increasing number of management strategies ranging from observation through to stem cell transplantation. There has been an exciting expansion in novel agents to treat FL, but at present there is not a universally accepted standard of care in the relapse setting. Decision-making can be difficult for the clinician as there is a paucity of data to compare the various relapse therapies available. This review will discuss conventional therapy for relapsed FL, consider the use of novel agents and explore the role and timing of autologous and allogeneic stem cell transplantation.