Navigation überspringen
Universitätsbibliothek Heidelberg
Status: Bibliographieeintrag

Verfügbarkeit
Standort: ---
Exemplare: ---
heiBIB
 Online-Ressource
Verfasst von:Geier, Johannes [VerfasserIn]   i
 Lessmann, Holger [VerfasserIn]   i
 Hillen, Uwe [VerfasserIn]   i
 Skudlik, Christoph [VerfasserIn]   i
 Jappe, Uta [VerfasserIn]   i
Titel:Sensitization to reactive diluents and hardeners in epoxy resin systems
Titelzusatz:IVDK data 2002-2011$dpart I: reaction frequencies
Verf.angabe:Johannes Geier, Holger Lessmann, Uwe Hillen, Christoph Skudlik and Uta Jappe
Jahr:2016
Jahr des Originals:2015
Umfang:11 S.
Fussnoten:First published: 05 November 2015 ; Gesehen am 22.05.2020
Titel Quelle:Enthalten in: Contact dermatitis
Ort Quelle:Oxford [u.a.] : Wiley-Blackwell, 1975
Jahr Quelle:2016
Band/Heft Quelle:74(2016), 2, Seite 83-93
ISSN Quelle:1600-0536
Abstract:BACKGROUND: Epoxy resin systems (ERSs), consisting of resins, reactive diluents, and hardeners, are indispensable in many branches of industry. In order to develop less sensitizing ERS formulations, knowledge of the sensitizing properties of single components is mandatory. - OBJECTIVES: To analyse the frequency of sensitization in the patients concerned, as one integral part of a research project on the sensitizing potency of epoxy resin compounds (FP-0324). - METHODS: A retrospective analysis of data from the Information Network of Departments of Dermatology (IVDK), 2002-2011, and a comparison of reaction frequencies with (surrogate) exposure data, were performed. - RESULTS: Almost half of the patients sensitized to epoxy resin were additionally sensitized to reactive diluents or hardeners. Among the reactive diluents, 1,6-hexanediol diglycidyl ether was the most frequent allergen, followed by 1,4-butanediol diglycidyl ether, phenyl glycidyl ether, and p-tert-butylphenyl glycidyl ether. Among the hardeners, m-xylylene diamine (MXDA) and isophorone diamine (IPDA) were the most frequent allergens. According to the calculated exposure-related frequency of sensitization, MXDA seems to be a far more important sensitizer than IPDA. Up to 60% of the patients sensitized to hardeners and 15-20% of those sensitized to reactive diluents do not react to epoxy resin. - CONCLUSIONS: In cases of suspected contact allergy to an ERS, a complete epoxy resin series must be patch tested from the start.
DOI:doi:10.1111/cod.12491
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext ; Verlag: https://doi.org/10.1111/cod.12490
 Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1111/cod.12490
 DOI: https://doi.org/10.1111/cod.12491
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:Adult
 Austria
 Butylene Glycols
 Dermatitis, Allergic Contact
 Dermatitis, Occupational
 Epoxy Compounds
 epoxy resin systems
 Epoxy Resins
 Female
 Germany
 Hand Dermatoses
 hardeners
 Humans
 Male
 Middle Aged
 occupational contact allergy
 Patch Tests
 reactive diluents
 Retrospective Studies
 Risk Factors
 Switzerland
 Young Adult
K10plus-PPN:1698678290
Verknüpfungen:→ Zeitschrift

Permanenter Link auf diesen Titel (bookmarkfähig):  https://katalog.ub.uni-heidelberg.de/titel/68579906   QR-Code
zum Seitenanfang