Non-dermatological challenges of chronic itch

• Verfasst von: Kremer, Andreas [VerfasserIn]
• Verfasst von: Mettang, Thomas [VerfasserIn]
• Verfasst von: Weisshaar, Elke [VerfasserIn]
• Titel: Non-dermatological challenges of chronic itch
• Verf.angabe: Andreas E. Kremer, Thomas Mettang and Elke Weisshaar
• E-Jahr: 2020
• Jahr: January 9, 2020
• Umfang: 6 S.
• Fussnoten: Gesehen am 04.06.2020
• Titel Quelle: Enthalten in: Acta dermato-venereologica
• Ort Quelle: Uppsala : Acta Dermato-Venereologica, 1946
• Jahr Quelle: 2020
• Band/Heft Quelle: 100(2020), 2, Artikel-ID adv00025
• ISSN Quelle: 1651-2057
• DOI: doi:10.2340/00015555-3345
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: acid
• Sach-SW: cholestasis
• Sach-SW: chronic pruritus
• Sach-SW: chronic kidney disease
• Sach-SW: european academy
• Sach-SW: forum edf
• Sach-SW: hydroxyethyl starch
• Sach-SW: liver
• Sach-SW: polycythemia-vera
• Sach-SW: primary biliary cholangitis
• Sach-SW: pruritus
• Sach-SW: quality-of-life
• Sach-SW: ruxolitinib
• Sach-SW: systemic disease
• Sach-SW: uraemic itch
• K10plus-PPN: 1699793158

Abstract

Chronic itch occurs in many skin diseases, but also in a variety of systemic, neurological, and psychogenic/psychosomatic disorders, or is caused by drug intake. When several diseases or causes co-exist, chronic itch is categorized as "mixed origin". These patients present with unaltered skin or with chronic scratch lesions including chronic prurigo. Precise diagnostics are necessary to evaluate the underlying aetiology, to enable identification of the best treatment available, and to improve patients' quality of life. This is of particular relevance in elderly people in whom chronic itch is often of systemic or mixed origin. Xerosis cutis is a frequent cofactor contributing to chronic itch of non-dermatological origin. Treatment is frequently multimodal, considering age, comorbidities, current drug intake, quality and intensity of itch. With regard to the demographic situation of the population, characterized by increasing life expectancy and polypharmacy, itch of non-dermatological origin will represent an increasing medical challenge in the future.