Short- and long-term effects of brain death on post-transplant graft function in a rodent model

• Verfasst von: Li, Shiliang [VerfasserIn]
• Verfasst von: Korkmaz-İçöz, Sevil [VerfasserIn]
• Verfasst von: Loganathan, Sivakkanan [VerfasserIn]
• Verfasst von: Radovits, Tamás [VerfasserIn]
• Verfasst von: Hegedűs, Péter [VerfasserIn]
• Verfasst von: Karck, Matthias [VerfasserIn]
• Verfasst von: Szabó, Gábor [VerfasserIn]
• Titel: Short- and long-term effects of brain death on post-transplant graft function in a rodent model
• Verf.angabe: Shiliang Li, Sevil Korkmaz, Sivakkanan Loganathan, Tamás Radovits, Peter Hegedűs, Matthias Karck and Gábor Szabó
• Jahr: 2015
• Jahr des Originals: 2014
• Umfang: 8 S.
• Fussnoten: Advance access publication 11 December 2014 ; Gesehen am 22.06.2020
• Titel Quelle: Enthalten in: Interactive cardiovascular and thoracic surgery
• Ort Quelle: Oxford : Oxford Univ. Press, 2002
• Jahr Quelle: 2015
• Band/Heft Quelle: 20(2015), 3, Seite 379-386
• ISSN Quelle: 1569-9285
• DOI: doi:10.1093/icvts/ivu403
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1701683555

Abstract

Heart transplantation has become the most effective treatment for end-stage heart failure. Donors after brain death (BD) are currently the only reliable source for cardiac transplants. However, haemodynamic instability and cardiac dysfunction have been demonstrated in brain-dead donors and this could therefore also affect post-transplant graft function. We studied the effects of BD on cardiac function and its short-term (1 h) or long-term (5 h) impacts on graft function.