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Verfasst von:Andrassy, Konrad [VerfasserIn]   i
Titel:Kidney and haemostasis
Verf.angabe:K. Andrassy
Jahr:2015
Jahr des Originals:2014
Umfang:4 S.
Fussnoten:Online: November 4, 2014 ; Gesehen am 23.07.2020
Titel Quelle:Enthalten in: Hämostaseologie
Ort Quelle:Stuttgart : Thieme, 1981
Jahr Quelle:2015
Band/Heft Quelle:35(2015), 01, Seite 73-76
ISSN Quelle:2567-5761
Abstract:<p>Renal insufficiency is characterized by thrombocytopathy, caused by the accumulation of water soluble and protein bound waste products of protein metabolism, which are not adequately eliminated by the kidney. The kidneys also excrete drugs and their metabolites, which accumulate if dosages are not adjusted to the renal function and may cause clinically relevant bleeding (i. e. synthetic penicillins, vitamin K antagonists, new oral anticoagulants). Therefore, each patients kidney function (GFR) ought to be evaluated by the KDIGO guidelines. The survival of chronic renal patients is lowered by increasing cardiovascular complications. Particularly frequent is non-valvular atrial fibrillation. The recommended prophylaxis with vitamin K antagonists for renal insufficiency is hampered by increased bleeding as well as by augmented (coronary) vascular and valvular calcification. It is not known yet whether prophylaxis with vitamin K may prevent this complication. <b>Conclusion:</b> Because new oral anticoagulants are equally or even more effective and cause less bleeding, they may be favoured in future and even in end-stage renal failure if more is known about dosing, safety and efficacy. The measurement of serum FGF 23 concentration may be helpful as a marker for their use.</p>
DOI:doi:10.5482/HAMO-14-08-0032
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext ; Verlag: https://doi.org/10.5482/HAMO-14-08-0032
 Volltext: http://www.thieme-connect.de/DOI/DOI?10.5482/HAMO-14-08-0032
 DOI: https://doi.org/10.5482/HAMO-14-08-0032
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:1725363585
Verknüpfungen:→ Zeitschrift

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