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| Verfasst von: | Wünnemann, Felix [VerfasserIn]  |
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| | Kintzelé, Laurent [VerfasserIn] |
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| | Braun, Alexander [VerfasserIn] |
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| | Zeifang, Felix [VerfasserIn] |
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| | Maier, Michael Wolfgang [VerfasserIn] |
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| | Burkholder, Iris [VerfasserIn] |
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| | Weber, Marc-André [VerfasserIn] |
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| | Kauczor, Hans-Ulrich [VerfasserIn] |
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| | Rehnitz, Christoph [VerfasserIn] |
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| Titel: | 3-T T2 mapping magnetic resonance imaging for biochemical assessment of normal and damaged glenoid cartilage |
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| Titelzusatz: | a prospective arthroscopy-controlled study |
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| Verf.angabe: | Felix Wuennemann, Laurent Kintzelé, Alexander Braun, Felix Zeifang, Michael W. Maier, Iris Burkholder, Marc-André Weber, Hans-Ulrich Kauczor & Christoph Rehnitz |
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| E-Jahr: | 2020 |
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| Jahr: | 01 September 2020 |
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| Umfang: | 11 S. |
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| Fussnoten: | Gesehen am 15.10.2020 |
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| Titel Quelle: | Enthalten in: Scientific reports |
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| Ort Quelle: | [London] : Macmillan Publishers Limited, part of Springer Nature, 2011 |
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| Jahr Quelle: | 2020 |
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| Band/Heft Quelle: | 10(2020) Artikel-Nummer 14396, 11 Seiten |
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| ISSN Quelle: | 2045-2322 |
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| Abstract: | This study evaluated the ability of T2 mapping to assess the glenoid cartilage using arthroscopy as the gold standard. Eighteen consecutive patients (mean age: 52.4 ± 14.72 years, including 12 men) with shoulder pain underwent T2 mapping at 3-T with subsequent shoulder arthroscopy. With correlation to cartilage-sensitive morphologic sequences regions-of-interest were placed in the corresponding T2 maps both in normal-appearing cartilage and focal cartilage lesions using a quadrant-wise approach. Inter-reader and intra-reader correlation coefficients (ICCs) between two independent radiologists as well as cut-off values with their sensitivities/specificities for the detection of cartilage damage were calculated. The mean T2 value for healthy cartilage was 23.0 ± 3 ms with significantly higher values in the superior quadrants compared to the inferior quadrants (p < 0.0001). In 5 patients with focal cartilage damage significantly higher T2 values of 44.7 ± 3.7 ms (P < 0.01) were observed. The maximum T2 value in normal cartilage (27.3 ms) was lower than the minimum value in damaged cartilage (40.8 ms) resulting in perfect sensitivities/specificities of 100% (95% confidence-interval 47.8-100.0) for all cut-off values between 27.3-40.8 ms. ICCs ranged between 0.63 and 0.99. In conclusion, T2 mapping can evaluate biochemical cartilage integrity and discriminates arthroscopy-proven healthy and damaged glenoid cartilage with high diagnostic performance. |
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| DOI: | doi:10.1038/s41598-020-71311-4 |
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| URL: | kostenfrei: Volltext: https://doi.org/10.1038/s41598-020-71311-4 |
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| | kostenfrei: Volltext: https://www.nature.com/articles/s41598-020-71311-4 |
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| | DOI: https://doi.org/10.1038/s41598-020-71311-4 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| K10plus-PPN: | 173563025X |
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| Verknüpfungen: | → Zeitschrift |
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| Lokale URL UB: |  Zum Volltext |
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3-T T2 mapping magnetic resonance imaging for biochemical assessment of normal and damaged glenoid cartilage / Wünnemann, Felix [VerfasserIn]; 01 September 2020 (Online-Ressource)
