| Online-Ressource |
Verfasst von: | Skopp, Gisela [VerfasserIn]  |
| Pötsch-Schneider, Lucia Edeltraud [VerfasserIn]  |
| Mauden, Jörg Martin [VerfasserIn]  |
Titel: | Stability of cannabinoids in hair samples exposed to sunlight |
Verf.angabe: | Gisela Skopp, Lucia Pötsch, and Martin Mauden |
E-Jahr: | 2000 |
Jahr: | 01 November 2000 |
Umfang: | 3 S. |
Teil: | volume:46 |
| year:2000 |
| number:11 |
| pages:1846-1848 |
| extent:3 |
Fussnoten: | Gesehen am 21.04.2021 |
Titel Quelle: | Enthalten in: Clinical chemistry |
Ort Quelle: | Washington, DC : American Association for Clinical Chemistry, 1955 |
Jahr Quelle: | 2000 |
Band/Heft Quelle: | 46(2000), 11, Seite 1846-1848 |
ISSN Quelle: | 1530-8561 |
Abstract: | The cannabinoid content in the hair samples was determined by gas chromatography-mass spectrometry. Each strand was pulverized in a ball mill, and ∼50 mg of the hair powder was weighed; 25 ng of THC-d3 (Radian International) was added as internal standard, and the sample was further processed according to Cirimele et al. (12). A 1-μL aliquot of the extract was injected into a gas chromatography-mass spectrometry system [HP 6890 gas chromatograph and HP 6890 mass spectrometer, both from Hewlett Packard; column, CP-Sil 5, 12.5 m × 0.53 mm (i.d.), from Chrompack]. Detection was by ionization in the electron impact mode (70 eV), with the scan mode set at single-ion monitoring (THC, m/z 299, 314, 271; THC-d3, m/z 302, 317, 274; CBN, m/z 295, 310, 238; CBD, m/z 231, 246, 314). Measurements were taken twice from each strand. The THC concentrations determined from a particular sample differed by at least 15% and are given as mean values (n = 4; Table 1 ). Deuterated standards for CBN and CDB are not yet commercially available; hence, these compounds were not quantified, and triplicate measurements of six drug-free hair samples were used to estimate their particular detection limits (mean + 3 SD). The limit of detection was 0.05 ng/mg of hair for all analytes. |
DOI: | doi:10.1093/clinchem/46.11.1846 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext ; Verlag: https://doi.org/10.1093/clinchem/46.11.1846 |
| Volltext: https://academic.oup.com/clinchem/article/46/11/1846/5641260 |
| DOI: https://doi.org/10.1093/clinchem/46.11.1846 |
Datenträger: | Online-Ressource |
Sprache: | eng |
K10plus-PPN: | 1755600771 |
Verknüpfungen: | → Zeitschrift |
Stability of cannabinoids in hair samples exposed to sunlight / Skopp, Gisela [VerfasserIn]; 01 November 2000 (Online-Ressource)