| |  Online-Ressource |
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| Verfasst von: | Huebner, Marianne [VerfasserIn]  |
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| | Börnigen, Daniela [VerfasserIn] |
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| | Deckert, Andreas [VerfasserIn] |
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| | Holle, Rolf [VerfasserIn] |
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| | Meisinger, Christa [VerfasserIn] |
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| | Müller-Nurasyid, Martina [VerfasserIn] |
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| | Peters, Annette [VerfasserIn] |
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| | Rathmann, Wolfgang [VerfasserIn] |
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| | Becher, Heiko [VerfasserIn] |
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| Titel: | Genetic variation and cardiovascular risk factors |
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| Titelzusatz: | a cohort study on migrants from the former Soviet Union and a native German Population |
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| Verf.angabe: | Marianne Huebner, Daniela Börnigen, Andreas Deckert, Rolf Holle, Christa Meisinger, Martina Müller-Nurasyid, Annette Peters, Wolfgang Rathmann and Heiko Becher |
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| E-Jahr: | 2021 |
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| Jahr: | 8 June 2021 |
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| Umfang: | 11 S. |
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| Teil: | volume:18 |
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| | year:2021 |
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| | number:12 |
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| | month:sp |
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| | elocationid:6215 |
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| | pages:1-11 |
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| | extent:11 |
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| Fussnoten: | Gesehen am 21.10.2021 |
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| Titel Quelle: | Enthalten in: International journal of environmental research and public health |
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| Ort Quelle: | Basel : MDPI AG, 2004 |
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| Jahr Quelle: | 2021 |
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| Band/Heft Quelle: | 18(2021), 12, Artikel-ID 6215, Seite 1-11 |
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| ISSN Quelle: | 1660-4601 |
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| Abstract: | Resettlers are a large migrant group of more than 2 million people in Germany who migrated mainly from the former Soviet Union to Germany after 1989. We sought to compare the distribution of the major risk factors for cardiovascular disease (CVD) and to investigate the overall genetic differences in a study population which consisted of resettlers and native (autochthone) Germans. This was a joint analysis of two cohort studies which were performed in the region of Augsburg, Bavaria, Germany, with 3363 native Germans and 363 resettlers. Data from questionnaires and physical examinations were used to compare the risk factors for cardiovascular diseases between the resettlers and native Germans. A population-based genome-wide association analysis was performed in order to identify the genetic differences between the two groups. The distribution of the major risk factors for CVD differed between the two groups. The resettlers lead a less active lifestyle. While female resettlers smoked less than their German counterparts, the men showed similar smoking behavior. SNPs from three genes (BTNL2, DGKB, TGFBR3) indicated a difference in the two populations. In other studies, these genes have been shown to be associated with CVD, rheumatoid arthritis and osteoporosis, respectively. |
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| DOI: | doi:10.3390/ijerph18126215 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext ; Verlag: https://doi.org/10.3390/ijerph18126215 |
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| | Volltext: https://www.mdpi.com/1660-4601/18/12/6215 |
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| | DOI: https://doi.org/10.3390/ijerph18126215 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | cardiovascular diseases |
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| | genetic differences |
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| | Germany |
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| | GWAS |
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| | lifestyle |
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| | migrants |
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| | resettlers |
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| K10plus-PPN: | 1774674610 |
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| Verknüpfungen: | → Zeitschrift |
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Genetic variation and cardiovascular risk factors / Huebner, Marianne [VerfasserIn]; 8 June 2021 (Online-Ressource)
