| Online-Ressource |
Verfasst von: | Bernardo Faura, Martí [VerfasserIn]  |
| Rinas, Melanie [VerfasserIn]  |
| Wirbel, Jakob [VerfasserIn]  |
| Pertsovskaya, Inna [VerfasserIn]  |
| Pliaka, Vicky [VerfasserIn]  |
| Messinis, Dimitris E. [VerfasserIn]  |
| Vila, Gemma [VerfasserIn]  |
| Sakellaropoulos, Theodore [VerfasserIn]  |
| Faigle, Wolfgang [VerfasserIn]  |
| Stridh, Pernilla [VerfasserIn]  |
| Behrens, Janina R. [VerfasserIn]  |
| Olsson, Tomas [VerfasserIn]  |
| Martin, Roland [VerfasserIn]  |
| Paul, Friedemann [VerfasserIn]  |
| Alexopoulos, Leonidas G. [VerfasserIn]  |
| Villoslada, Pablo [VerfasserIn]  |
| Sáez Rodríguez, Julio [VerfasserIn]  |
Titel: | Prediction of combination therapies based on topological modeling of the immune signaling network in multiple sclerosis |
Verf.angabe: | Marti Bernardo-Faura, Melanie Rinas, Jakob Wirbel, Inna Pertsovskaya, Vicky Pliaka, Dimitris E. Messinis, Gemma Vila, Theodore Sakellaropoulos, Wolfgang Faigle, Pernilla Stridh, Janina R. Behrens, Tomas Olsson, Roland Martin, Friedemann Paul, Leonidas G. Alexopoulos, Pablo Villoslada and Julio Saez-Rodriguez |
E-Jahr: | 2021 |
Jahr: | 16 July 2021 |
Umfang: | 16 S. |
Fussnoten: | Gesehen am 28.10.2021 |
Titel Quelle: | Enthalten in: Genome medicine |
Ort Quelle: | London : BioMed Central, 2009 |
Jahr Quelle: | 2021 |
Band/Heft Quelle: | 13(2021), Artikel-ID 117, Seite 1-16 |
ISSN Quelle: | 1756-994X |
Abstract: | Multiple sclerosis (MS) is a major health problem, leading to a significant disability and patient suffering. Although chronic activation of the immune system is a hallmark of the disease, its pathogenesis is poorly understood, while current treatments only ameliorate the disease and may produce severe side effects. |
DOI: | doi:10.1186/s13073-021-00925-8 |
URL: | kostenfrei: Volltext: https://doi.org/10.1186/s13073-021-00925-8 |
| DOI: https://doi.org/10.1186/s13073-021-00925-8 |
Datenträger: | Online-Ressource |
Sprache: | eng |
Sach-SW: | Combination therapy |
| Immunotherapy |
| Kinases |
| Logic modeling |
| Multiple sclerosis |
| Network modeling |
| Pathways |
| Personalized medicine |
| Phosphoproteomics |
| Signaling networks |
| Treatment |
| xMAP assay |
K10plus-PPN: | 1775623785 |
Verknüpfungen: | → Zeitschrift |
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Lokale URL UB: | Zum Volltext |
Prediction of combination therapies based on topological modeling of the immune signaling network in multiple sclerosis / Bernardo Faura, Martí [VerfasserIn]; 16 July 2021 (Online-Ressource)