Limited Plasmodium sporozoite gliding motility in the absence of TRAP family adhesins

• Verfasst von: Beyer, Konrad [VerfasserIn]
• Verfasst von: Kracht, Simon [VerfasserIn]
• Verfasst von: Kehrer, Jessica [VerfasserIn]
• Verfasst von: Singer, Mirko [VerfasserIn]
• Verfasst von: Klug, Dennis [VerfasserIn]
• Verfasst von: Frischknecht, Friedrich [VerfasserIn]
• Titel: Limited Plasmodium sporozoite gliding motility in the absence of TRAP family adhesins
• Verf.angabe: Konrad Beyer, Simon Kracht, Jessica Kehrer, Mirko Singer, Dennis Klug and Friedrich Frischknecht
• E-Jahr: 2021
• Jahr: 30 October 2021
• Umfang: 12 S.
• Fussnoten: Gesehen am 13.12.2021
• Titel Quelle: Enthalten in: Malaria journal
• Ort Quelle: London : BioMed Central, 2002
• Jahr Quelle: 2021
• Band/Heft Quelle: 20(2021), Artikel-ID 430, Seite 1-12
• ISSN Quelle: 1475-2875
• DOI: doi:10.1186/s12936-021-03960-3
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: Adhesion
• Sach-SW: Anopheles
• Sach-SW: Malaria
• Sach-SW: Migration
• Sach-SW: Transmission
• K10plus-PPN: 1782025782
• K10plus-PPN:
  Universitätsbibliothek
• Lokale URL UB: Zum Volltext

Abstract

Plasmodium sporozoites are the highly motile forms of malaria-causing parasites that are transmitted by the mosquito to the vertebrate host. Sporozoites need to enter and cross several cellular and tissue barriers for which they employ a set of surface proteins. Three of these proteins are members of the thrombospondin related anonymous protein (TRAP) family. Here, potential additive, synergistic or antagonistic roles of these adhesion proteins were investigated.