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| Verfasst von: | Janda, Ales̆ [VerfasserIn]  |
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| | Engel, Corinna [VerfasserIn] |
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| | Remppis, Jonathan [VerfasserIn] |
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| | Enkel, Sigrid [VerfasserIn] |
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| | Peter, Andreas [VerfasserIn] |
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| | Hörber, Sebastian [VerfasserIn] |
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| | Ganzenmueller, Tina [VerfasserIn] |
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| | Schober, Sarah [VerfasserIn] |
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| | Weinstock, Christof [VerfasserIn] |
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| | Jacobsen, Eva-Maria [VerfasserIn] |
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| | Fabricius, Dorit [VerfasserIn] |
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| | Zernickel, Maria [VerfasserIn] |
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| | Stamminger, Thomas [VerfasserIn] |
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| | Dietz, Andrea [VerfasserIn] |
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| | Groß, Hans-Jürgen [VerfasserIn] |
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| | Bode, Sebastian F. N. [VerfasserIn] |
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| | Haddad, Anneke D. M. [VerfasserIn] |
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| | Elling, Roland [VerfasserIn] |
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| | Stich, Maximilian [VerfasserIn] |
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| | Tönshoff, Burkhard [VerfasserIn] |
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| | Henneke, Philipp [VerfasserIn] |
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| | Debatin, Klaus-Michael [VerfasserIn] |
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| | Franz, Axel R. [VerfasserIn] |
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| | Renk, Hanna [VerfasserIn] |
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| Titel: | Role of ABO blood group in SARS-CoV-2 infection in households |
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| Verf.angabe: | Ales Janda, Corinna Engel, Jonathan Remppis, Sigrid Enkel, Andreas Peter, Sebastian Hörber, Tina Ganzenmueller, Sarah Schober, Christof Weinstock, Eva-Maria Jacobsen, Dorit Fabricius, Maria Zernickel, Thomas Stamminger, Andrea Dietz, Hans-Jürgen Groß, Sebastian F.N. Bode, Anneke D.M. Haddad, Roland Elling, Maximilian Stich, Burkhard Tönshoff, Philipp Henneke, Klaus-Michael Debatin, Axel R. Franz and Hanna Renk |
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| E-Jahr: | 2022 |
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| Jahr: | 06 May 2022 |
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| Umfang: | 8 S. |
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| Fussnoten: | Gesehen am 20.07.2022 |
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| Titel Quelle: | Enthalten in: Frontiers in microbiology |
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| Ort Quelle: | Lausanne : Frontiers Media, 2010 |
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| Jahr Quelle: | 2022 |
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| Band/Heft Quelle: | 13(2022) vom: Mai, Artikel-ID 857965, Seite 1-8 |
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| ISSN Quelle: | 1664-302X |
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| Abstract: | An association between certain ABO/Rh blood groups and susceptibility to SARS-CoV-2 infection has been proposed for adults, although this remains controversial. In children and adolescents, the relationship is unclear due to a lack of robust data. Here, we investigated the association of ABO/Rh blood groups and SARS-CoV-2 in a multi-center study comprising 163 households with 281 children and 355 adults and at least one SARS-CoV-2 seropositive individual as determined by three independent assays as a proxy for previous infection. In line with previous findings, we found a higher frequency of blood group A (+ 6%) and a lower frequency of blood group O (−6%) among the SARS-CoV-2 seropositive adults compared to the seronegative ones. This trend was not seen in children. In contrast, SARS-CoV-2 seropositive children had a significantly lower frequency of Rh-positive blood groups. ABO compatibility did not seem to play a role in SARS-CoV-2 transmission within the families. A correction for family clusters was performed and estimated fixed effects of the blood group on the risk of SARS-CoV-2 seropositivity and symptomatic infection were determined. Although we found a different distribution of blood groups in seropositive individuals compared to the reference population, the risk of SARS-CoV-2 seropositivity or symptomatic infection was not increased in children or in adults with blood group A or AB versus O or B. Increasing age was the only parameter positively correlating with the risk of SARS-CoV-2 infection. In conclusion, specific ABO/Rh blood groups and ABO compatibility appear not to predispose for SARS-CoV-2 susceptibility in children. |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://www.frontiersin.org/articles/10.3389/fmicb.2022.857965 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| K10plus-PPN: | 1811015921 |
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| Verknüpfungen: | → Zeitschrift |
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Role of ABO blood group in SARS-CoV-2 infection in households / Janda, Ales̆ [VerfasserIn]; 06 May 2022 (Online-Ressource)
