Body fluid derived exosomes as a novel template for clinical diagnostics

• Verfasst von: Keller, Sascha [VerfasserIn]
• Verfasst von: Ridinger, Johannes [VerfasserIn]
• Verfasst von: Rupp, Anne-Kathleen [VerfasserIn]
• Verfasst von: Janssen, Johannes W. G. [VerfasserIn]
• Verfasst von: Altevogt, Peter [VerfasserIn]
• Titel: Body fluid derived exosomes as a novel template for clinical diagnostics
• Verf.angabe: Sascha Keller, Johannes Ridinger, Anne-Kathleen Rupp, Johannes WG Janssen and Peter Altevogt
• E-Jahr: 2011
• Jahr: 8 June 2011
• Umfang: 9 S.
• Fussnoten: Gesehen am 28.07.2022
• Titel Quelle: Enthalten in: Journal of translational medicine
• Ort Quelle: London : BioMed Central, 2003
• Jahr Quelle: 2011
• Band/Heft Quelle: 9(2011), Artikel-ID 86, Seite 1-9
• ISSN Quelle: 1479-5876
• DOI: doi:10.1186/1479-5876-9-86
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: Amniotic Fluid
• Sach-SW: Exosomal Protein
• Sach-SW: Giant Cell Arteritis
• Sach-SW: Latex Bead
• Sach-SW: Malignant Ascites
• K10plus-PPN: 1811901395

Abstract

Exosomes are small membrane vesicles with a size of 40-100 nm that are released by different cell types from a late endosomal cellular compartment. They can be found in various body fluids including plasma, malignant ascites, urine, amniotic fluid and saliva. Exosomes contain proteins, miRNAs and mRNAs (exosome shuttle RNA, esRNA) that could serve as novel platform for diagnosis.