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Verfasst von:Brost, Sylvia [VerfasserIn]   i
 Wenzel, J. J. [VerfasserIn]   i
 Ganten, Tom M. [VerfasserIn]   i
 Filser, Michael [VerfasserIn]   i
 Flechtenmacher, Christa [VerfasserIn]   i
 Boehm, S. [VerfasserIn]   i
 Astani, Akram [VerfasserIn]   i
 Jilg, W. [VerfasserIn]   i
 Zeier, Martin [VerfasserIn]   i
 Schnitzler, Paul [VerfasserIn]   i
Titel:Sporadic cases of acute autochthonous hepatitis E virus infection in Southwest Germany
Verf.angabe:S. Brost, J.J. Wenzel, T.M. Ganten, M. Filser, C. Flechtenmacher, S. Boehm, A. Astani, W. Jilg, M. Zeier, P. Schnitzler
Jahr:2010
Umfang:4 S.
Fussnoten:Erstmals am 11. November 2009 online veröffentlicht ; Gesehen am 01.03.2023
Titel Quelle:Enthalten in: Clinical and diagnostic virology
Ort Quelle:Amsterdam [u.a.] : Elsevier Science, 1993
Jahr Quelle:2010
Band/Heft Quelle:47(2010), 1 vom: Jan., Seite 89-92
ISSN Quelle:1873-4901
Abstract:Hepatitis E infection is usually a self-limiting disease and an important cause of acute hepatitis in tropical and subtropical regions where the virus is endemic. In industrialized countries, sporadic cases of acute hepatitis E virus (HEV) infections have been described and the number of documented autochthonous infections seems to be increasing. We report three sporadic cases of autochthonous hepatitis E infections in Southwestern Germany which presented at our university hospital within two years. All cases were men who presented with acute hepatitis, icterus and elevated liver. In case 1 and case 2, liver biopsy revealed acute hepatitis, both patients were positive for anti-HEV antibodies, case 1 was also positive for HEV RNA with a viral load of 3.0×103copies/ml in serum. In case 3, anti-HEV antibodies were detectable and HEV RNA was detected in serum (4.3×103copies/ml) and stool (1.4×106copies/ml). None of the patients had a recent travel history outside Germany and close contact to animals has been denied. HEV sequence analysis of two patients revealed genotype 3 with homologies to other European isolates and isolates from swine. Thus the source of infection remains unclear. Hepatitis E should be considered in differential diagnosis in patients with unexplained hepatitis and patients with acute hepatitis, whatever their age or travel history might be, should be tested for HEV.
DOI:doi:10.1016/j.jcv.2009.10.011
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.1016/j.jcv.2009.10.011
 Volltext: https://www.sciencedirect.com/science/article/pii/S1386653209005010
 DOI: https://doi.org/10.1016/j.jcv.2009.10.011
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:Acute hepatitis
 Autochthonous hepatitis E
 Hepatitis E virus
 HEV
K10plus-PPN:1837834040
Verknüpfungen:→ Zeitschrift

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