| |  Online resource |
|---|
| Verfasst von: | Monostori, Péter [VerfasserIn]  |
|---|
| | Godejohann, Markus [VerfasserIn] |
|---|
| | Janda, Joachim [VerfasserIn] |
|---|
| | Galla, Zsolt [VerfasserIn] |
|---|
| | Rácz, Gábor [VerfasserIn] |
|---|
| | Klinke, Glynis [VerfasserIn] |
|---|
| | Szatmári, Ildikó [VerfasserIn] |
|---|
| | Zsidegh, Petra [VerfasserIn] |
|---|
| | Kohlmüller, Dirk [VerfasserIn] |
|---|
| | Kölker, Stefan [VerfasserIn] |
|---|
| | Hoffmann, Georg F. [VerfasserIn] |
|---|
| | Gramer, Gwendolyn [VerfasserIn] |
|---|
| | Okun, Jürgen G. [VerfasserIn] |
|---|
| Titel: | Identification of potential interferents of methylmalonic acid |
|---|
| Titelzusatz: | a previously unrecognized pitfall in clinical diagnostics and newborn screening |
|---|
| Verf.angabe: | Péter Monostori, Markus Godejohann, Joachim Janda, Zsolt Galla, Gábor Rácz, Glynis Klinke, Ildikó Szatmári, Petra Zsidegh, Dirk Kohlmüller, Stefan Kölker, Georg F. Hoffmann, Gwendolyn Gramer, Jürgen G. Okun |
|---|
| Jahr: | 2023 |
|---|
| Umfang: | 9 S. |
|---|
| Illustrationen: | Diagramme |
|---|
| Fussnoten: | Online veröffentlicht am 3. Oktober 2022 ; Gesehen am 16.11.2023 |
|---|
| Titel Quelle: | Enthalten in: Clinical biochemistry |
|---|
| Ort Quelle: | Amsterdam [u.a.] : Elsevier Science, 1967 |
|---|
| Jahr Quelle: | 2023 |
|---|
| Band/Heft Quelle: | 111(2023) vom: Jan., Seite 72-80 |
|---|
| ISSN Quelle: | 1873-2933 |
|---|
| Abstract: | Determination of methylmalonic acid (MMA) from dried blood spots (DBS) is commonly performed in clinical diagnostics and newborn screening for propionic acidemia (PA) and methylmalonic acidemia. Isobaric compounds of MMA having the same mass can affect diagnostic reliability and quantitative results, which represents a previously unrecognized pitfall in clinical assays for MMA. We set out to identify interfering substances of MMA in DBS, serum and urine samples from confirmed patients with PA and methylmalonic acidemia. |
|---|
| DOI: | doi:10.1016/j.clinbiochem.2022.09.010 |
|---|
| URL: | Bibliographic entry. University members only receive access to full-texts for open access or licensed publications.
Volltext: https://doi.org/10.1016/j.clinbiochem.2022.09.010 |
|---|
| | Volltext: https://www.sciencedirect.com/science/article/pii/S0009912022002247 |
|---|
| | DOI: https://doi.org/10.1016/j.clinbiochem.2022.09.010 |
|---|
| Datenträger: | Online-Ressource |
|---|
| Sprache: | eng |
|---|
| Sach-SW: | Diagnostic reliability |
|---|
| | Interfering substance |
|---|
| | Mass spectrometry |
|---|
| | Metabolic disorder |
|---|
| | Methylmalonic acid |
|---|
| | Newborn screening |
|---|
| K10plus-PPN: | 1839345063 |
|---|
| Verknüpfungen: | → Journal |
|---|
Identification of potential interferents of methylmalonic acid / Monostori, Péter [VerfasserIn]; 2023 (Online-Ressource)
