| |  Online-Ressource |
|---|
| Verfasst von: | Heumann, Philipp [VerfasserIn]  |
|---|
| | Aguado-Barrera, Miguel E. [VerfasserIn] |
|---|
| | Avuzzi, Barbara [VerfasserIn] |
|---|
| | Azria, David [VerfasserIn] |
|---|
| | Briers, Erik [VerfasserIn] |
|---|
| | Bultijnck, Renée [VerfasserIn] |
|---|
| | Choudhury, Ananya [VerfasserIn] |
|---|
| | De Ruysscher, Dirk [VerfasserIn] |
|---|
| | Farcy-Jacquet, Marie-Pierre [VerfasserIn] |
|---|
| | Fonteyne, Valérie [VerfasserIn] |
|---|
| | Gómez Caamaño, Antonio [VerfasserIn] |
|---|
| | Helmbold, Irmgard [VerfasserIn] |
|---|
| | Johnson, Kerstie [VerfasserIn] |
|---|
| | Kerns, Sarah L. [VerfasserIn] |
|---|
| | Lambrecht, Maarten [VerfasserIn] |
|---|
| | Lingard, Zoe [VerfasserIn] |
|---|
| | Rancati, Tiziana [VerfasserIn] |
|---|
| | Rosenstein, Barry S. [VerfasserIn] |
|---|
| | Sperk, Elena [VerfasserIn] |
|---|
| | Paul Symonds, R. [VerfasserIn] |
|---|
| | Talbot, Christopher [VerfasserIn] |
|---|
| | Valdagni, Riccardo [VerfasserIn] |
|---|
| | Vega, Ana [VerfasserIn] |
|---|
| | Veldeman, Liv [VerfasserIn] |
|---|
| | Ward, Tim [VerfasserIn] |
|---|
| | Webb, Adam [VerfasserIn] |
|---|
| | West, Catharine M. [VerfasserIn] |
|---|
| | Chang-Claude, Jenny [VerfasserIn] |
|---|
| | Seibold, Petra [VerfasserIn] |
|---|
| Titel: | Comparing symptom reporting by prostate cancer patients and healthcare professionals in the international multicentre REQUITE study |
|---|
| Verf.angabe: | Philipp Heumann, Miguel E. Aguado-Barrera, Barbara Avuzzi, David Azria, Erik Briers, Renée Bultijnck, Ananya Choudhury, Dirk De Ruysscher, Marie-Pierre Farcy-Jacquet, Valérie Fonteyne, Antonio Gómez Caamaño, Irmgard Helmbold, Kerstie Johnson, Sarah L. Kerns, Maarten Lambrecht, Zoe Lingard, Tiziana Rancati, Barry S. Rosenstein, Elena Sperk, R. Paul Symonds, Christopher Talbot, Riccardo Valdagni, Ana Vega, Liv Veldeman, Tim Ward, Adam Webb, Catharine M. West, Jenny Chang-Claude, Petra Seibold, on behalf of the REQUITE Consortium |
|---|
| E-Jahr: | 2023 |
|---|
| Jahr: | January 2023 |
|---|
| Umfang: | 10 S. |
|---|
| Fussnoten: | Online verfügbar 25. November 2022, Artikelversion 8. Dezember 2022 ; Gesehen am 06.04.2023 |
|---|
| Titel Quelle: | Enthalten in: Radiotherapy and oncology |
|---|
| Ort Quelle: | Amsterdam [u.a.] : Elsevier Science, 1983 |
|---|
| Jahr Quelle: | 2023 |
|---|
| Band/Heft Quelle: | 178(2023) vom: Jan., Artikel-ID 109426, Seite 1-10 |
|---|
| ISSN Quelle: | 1879-0887 |
|---|
| Abstract: | Introduction - Previous studies showed that healthcare professionals and patients had only moderate to low agreement on their assessment of treatment-related symptoms. We aimed to determine the levels of agreement in a large cohort of prostate cancer patients. - Methods - Analyses were made of data from 1,756 prostate cancer patients treated with external beam radiotherapy (RT) and/or brachytherapy in Europe and the USA and recruited into the prospective multicentre observational REQUITE study. Eleven pelvic symptoms at the end of RT were compared after translating patient-reported outcomes (PROs) into CTCAE-based healthcare professional ratings. Gwet's AC2 agreement coefficient and 95% confidence intervals were calculated for each symptom. To compare severity of grading between patients and healthcare professionals, percent agreement and deviations for each symptom were graphically depicted. Stratified and sensitivity analyses were conducted to identify potential influencing factors and to assess heterogeneity and robustness of results. - Results - The agreement for the 11 pelvic symptoms varied from very good (AC2 > 0.8: haematuria, rectal bleeding, management of sphincter control) to poor agreement (AC2 ≤ 0.2: proctitis and urinary urgency). Fatigue had a negative impact on the agreement. Patients tended to grade symptoms more severely than healthcare professionals. Information on sexual dysfunction was missing more frequently in healthcare professional assessment than PROs. - Conclusion - Agreement was better for observable than subjective symptoms, with patients usually grading symptoms more severely than healthcare professionals. Our findings emphasize that PROs should complement symptom assessment by healthcare professionals and be taken into consideration for clinical decision-making to incorporate the patient perspective. |
|---|
| DOI: | doi:10.1016/j.radonc.2022.11.015 |
|---|
| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1016/j.radonc.2022.11.015 |
|---|
| | Volltext: https://www.sciencedirect.com/science/article/pii/S0167814022045637 |
|---|
| | DOI: https://doi.org/10.1016/j.radonc.2022.11.015 |
|---|
| Datenträger: | Online-Ressource |
|---|
| Sprache: | eng |
|---|
| Sach-SW: | Adverse events |
|---|
| | Agreement |
|---|
| | Patient-reported outcomes |
|---|
| | Prostate cancer |
|---|
| | Radiotherapy |
|---|
| K10plus-PPN: | 1841862916 |
|---|
| Verknüpfungen: | → Zeitschrift |
|---|
Comparing symptom reporting by prostate cancer patients and healthcare professionals in the international multicentre REQUITE study / Heumann, Philipp [VerfasserIn]; January 2023 (Online-Ressource)
