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Verfasst von:Reichrath, Jörg [VerfasserIn]   i
 März, Winfried [VerfasserIn]   i
 Gruijl, Frank R. De [VerfasserIn]   i
 Vieth, Reinhold [VerfasserIn]   i
 Grant, William B. [VerfasserIn]   i
 Slominski, Andrzej T. [VerfasserIn]   i
 Holick, Michael F. [VerfasserIn]   i
 Vogt, Thomas [VerfasserIn]   i
 Pilz, Stefan [VerfasserIn]   i
Titel:An appraisal to address health consequences of Vitamin D deficiency with food fortification and supplements
Titelzusatz:time to act!
Verf.angabe:Jörg Reichrath, Winfried März, Frank R. De Gruijl, Reinhold Vieth, William B. Grant, Andrzej T. Slominski, Michael F. Holick, Thomas Vogt and Stefan Pilz
E-Jahr:2022
Jahr:October 2022
Umfang:7 S.
Fussnoten:Gesehen am 22.08.2023
Titel Quelle:Enthalten in: Anticancer research
Ort Quelle:Kapandriti, Attiki, Greece : International Institute of Anticancer Research, 2004
Jahr Quelle:2022
Band/Heft Quelle:42(2022), 10 vom: Okt., Seite 5009-5015
ISSN Quelle:1791-7530
Abstract:A symposium entitled “Vitamin D in Prevention and Therapy” was held on May 4-5, 2022, in Homburg, Germany to discuss important new advances in the field, including identification of new vitamin D signaling pathways, of new biologic effects of vitamin D-compounds (e.g., on the microbiome), and convincing proof of the relevance of vitamin D deficiency for the risk and outcome of many chronic diseases, including cancer, cardio-vascular, auto-immune, metabolic, and infectious diseases. Concerning the COVID-19-pandemic, an inverse association between 25(OH)D serum concentrations and SARS-CoV-2-infections, morbidity, and mortality was shown. In relation to cancer, several meta-analyses recently demonstrated an association of vitamin D-supplementation with significantly decreased mortality rates, which presumably would reduce health care costs. Considering the impressive body of evidence and the high safety of oral supplementation and food fortification with vitamin D, it was concluded that there is now an urgent need to act. In many countries worldwide, health care authorities need to increase efforts to address vitamin D deficiency, e.g., via food fortification and/or supplementation with vitamin D, and/or promoting moderate UV-exposure. It was estimated that in many countries, vitamin D intakes of the order of appr. 1,000 IE (25 μg)/day would be needed to bring and/or keep the vast majority of people over a serum 25(OH)D threshold of 20 ng/ml (50 nmol/l), which would be difficult to obtain alone from food fortification. New developments in personalized medicine may represent helpful tools to identify populations at risk for vitamin D deficiency and their responsiveness to vitamin D treatment.
DOI:doi:10.21873/anticanres.16008
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.21873/anticanres.16008
 Volltext: https://ar.iiarjournals.org/content/42/10/5009
 DOI: https://doi.org/10.21873/anticanres.16008
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:25-hydroxyvitamin D serum concentration
 food fortification
 review
 supplementation
 Vitamin D deficiency
 vitamin D status
K10plus-PPN:1856827879
Verknüpfungen:→ Zeitschrift

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