Status: Bibliographieeintrag
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| |  Online-Ressource |
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| Verfasst von: | Weller, Frédéric [VerfasserIn]  |
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| Titel: | A free boundary problem modeling thrombus growth |
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| Verf.angabe: | Frédéric Frank Weller |
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| E-Jahr: | 2010 |
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| Jahr: | 7 January 2010 |
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| Umfang: | 14 S. |
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| Fussnoten: | Gesehen am 25.10.2023 |
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| Titel Quelle: | Enthalten in: Journal of mathematical biology |
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| Ort Quelle: | Berlin : Springer, 1974 |
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| Jahr Quelle: | 2010 |
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| Band/Heft Quelle: | 61(2010), 6, Seite 805-818 |
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| ISSN Quelle: | 1432-1416 |
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| Abstract: | Recently, neglect of either shear stress, surface saturation, or thrombus growth in mathematical models of platelet deposition has been identified as leading cause of inability to match experimental evidence. While the consideration of shear stress is necessary to obtain at least some qualitative agreement, purely shear-dependent approaches yield notable quantitative discrepancies. In a previous paper, the author demonstrated that surface saturation significantly improves model predictions. However, discrepancies still persist when thrombus growth is neglected. Therefore, the present work develops a free boundary problem which takes this into account. Numerical simulations are performed using the level set method. The results agree well with measurements in stagnation point flow and tubular expansions, which demonstrates the coupling of flow, platelet adhesion, and aggregate growth in primary hemostasis. |
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| DOI: | doi:10.1007/s00285-009-0324-1 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1007/s00285-009-0324-1 |
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| | Volltext: https://link.springer.com/article/10.1007/s00285-009-0324-1 |
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| | DOI: https://doi.org/10.1007/s00285-009-0324-1 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | 35R35 |
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| | 35R37 |
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| | 76D05 |
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| | 76Z05 |
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| | 92-08 |
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| | 92C10 |
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| | Fluid dynamics |
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| | Free boundary problem |
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| | Level set method |
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| | Shear stress |
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| | Thrombus growth |
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| K10plus-PPN: | 1867632586 |
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| Verknüpfungen: | → Zeitschrift |
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¬A¬ free boundary problem modeling thrombus growth / Weller, Frédéric [VerfasserIn]; 7 January 2010 (Online-Ressource)
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