| Online-Ressource |
Verfasst von: | Hösl, Michaela [VerfasserIn]  |
| Schad, Lothar R. [VerfasserIn]  |
| Rapacchi, Stanislas [VerfasserIn]  |
Titel: | Volumetric 23Na single and triple-quantum Imaging at 7T: 3D-CRISTINA |
Verf.angabe: | Michaela A.U. Hoesl, Lothar R. Schad, Stanislas Rapacchi |
E-Jahr: | 2022 |
Jahr: | May 2022 |
Umfang: | 10 S. |
Illustrationen: | Illustrationen |
Fussnoten: | Online verfügbar: 26. Oktober 2021, Artikelversion: 29. Mai 2022 ; Im Titel ist die Zahl 23 bei "23Na" hochgestellt ; Gesehen am 20.02.2024 |
Titel Quelle: | Enthalten in: Zeitschrift für medizinische Physik |
Ort Quelle: | Amsterdam [u.a.] : Elsevier, 1990 |
Jahr Quelle: | 2022 |
Band/Heft Quelle: | 32(2022), 2 vom: Mai, Seite 199-208 |
ISSN Quelle: | 1876-4436 |
Abstract: | Purpose - To measure multi-quantum coherence (MQC) 23Na signals for noninvasive cell physiological information in the whole-brain, the 2D-CRISTINA method was extended to 3D. This experimental study investigated the use and results of a new sequence, 3D-CRISTINA, on a phantom and healthy volunteers. - Methods - The 3D Cartesian single and triple-quantum imaging of 23Na (3D-CRISTINA) was developed and implemented at 7T, favoring a non-selective volume excitation for increased signal-to-noise ratio (SNR) and lower energy deployment than its 2D counterpart. Two independent phase cycles were used in analogy to the 2D method. A comparison of 6-steps cycles and 12-steps cycles was performed. We used a phantom composed of different sodium and agarose concentrations, 50mM to 150mM Na+, and 0-5% agarose for sequence validation. Four healthy volunteers were scanned at 7T for whole brain MQC imaging. The sequence 3D-CRISTINA was developed and tested at 7T. - Results - At 7T, the 3D-CRISTINA acquisition allowed to reduce the TR to 230ms from the previous 390ms for 2D, resulting in a total acquisition time of 53min for a 3D volume of 4×4×8mm resolution. The phase cycle evaluation showed that the 7T acquisition time could be reduced by 4-fold with moderate single and triple-quantum signals SNR loss. The healthy volunteers demonstrated clinical feasibility at 7T and showed a difference in the MQC signals ratio of White Matter (WM) and Grey Matter (GM). - Conclusion - Volumetric CRISTINA multi-quantum imaging allowed whole-brain coverage. The non-selective excitation enabled a faster scan due to a decrease in energy deposition which enabled a lower repetition time. Thus, it should be the preferred choice for future in vivo multi-quantum applications compared to the 2D method. A more extensive study is warranted to explore WM and GM MQC differences. |
DOI: | doi:10.1016/j.zemedi.2021.09.001 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
kostenfrei: Volltext: https://doi.org/10.1016/j.zemedi.2021.09.001 |
| kostenfrei: Volltext: https://www.sciencedirect.com/science/article/pii/S0939388921000830 |
| DOI: https://doi.org/10.1016/j.zemedi.2021.09.001 |
Datenträger: | Online-Ressource |
Sprache: | eng |
Bibliogr. Hinweis: | Errata: Hösl, Michaela, 1989 - : Erratum to “Volumetric 23Na single and triple-quantum imaging at 7T |
Sach-SW: | Sodium MRI |
| Sodium triple-quantum imaging |
| Whole-brain imaging |
K10plus-PPN: | 1881216829 |
Verknüpfungen: | → Zeitschrift |
Volumetric 23Na single and triple-quantum Imaging at 7T: 3D-CRISTINA / Hösl, Michaela [VerfasserIn]; May 2022 (Online-Ressource)