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Status: Bibliographieeintrag

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Verfasst von:Salbach, Christian [VerfasserIn]   i
 Yildirim, Mustafa [VerfasserIn]   i
 Hund, Hauke [VerfasserIn]   i
 Biener, Moritz [VerfasserIn]   i
 Müller-Hennessen, Matthias [VerfasserIn]   i
 Frey, Norbert [VerfasserIn]   i
 Katus, Hugo [VerfasserIn]   i
 Giannitsis, Evangelos [VerfasserIn]   i
 Milles, Barbara Ruth [VerfasserIn]   i
Titel:Design, rationale and initial findings from HERA‐FIB on 10 222 patients with atrial fibrillation presenting to an emergency department over an 11‐year period
Verf.angabe:Christian Salbach, Mustafa Yildirim, Hauke Hund, Moritz Biener, Matthias Müller‐Hennessen, Norbert Frey, Hugo A. Katus, Evangelos Giannitsis, Barbara Ruth Milles
E-Jahr:2024
Jahr:7 May 2024
Umfang:13 S.
Fussnoten:Gesehen am 30.09.2024
Titel Quelle:Enthalten in: American Heart AssociationJournal of the American Heart Association
Ort Quelle:New York, NY : Association, 2012
Jahr Quelle:2024
Band/Heft Quelle:13(2024), 9, Artikel-ID e033396, Seite e033396-1-e033396-13
ISSN Quelle:2047-9980
Abstract:For the majority of patients with atrial fibrillation (AF), disease management has improved in recent years. However, there are still populations underrepresented or excluded in current registries and randomized controlled trials. HERA‐FIB (Heidelberg Registry of Atrial Fibrillation) was planned to assess real‐world evidence for the prevalence, demographic characteristics and management of patients with the diagnosis of AF presenting consecutively to a chest pain unit.Methods and ResultsHERA‐FIB is a retrospective, observational, single‐center study on patients with a diagnosis of AF presenting to a chest pain unit from June 2009 until March 2020. This article describes the structure, governance, outcome assessment, quality and data collection processes of the registry. Additionally, characteristics of populations of special interest are described. The study consecutively enrolled 10 222 patients presenting with AF to the chest pain unit of the University Hospital of Heidelberg. Clinical parameters and patient characteristics were assessed retrospectively. Outcome parameters included rates for all‐cause death, stroke, myocardial infarction and major bleedings. We were able to investigate patient cohorts of special interest such as advanced chronic kidney disease, octogenarians, and those with acute coronary syndrome who are often underrepresented in current studies and randomized controlled trials.ConclusionsHERA‐FIB is one of the largest real‐world single‐center retrospective registries on patients with AF, which captures the era of transition from vitamin K antagonists to non-vitamin K oral anticoagulation regimens in clinical practice and offers the possibility to investigate patient populations usually underrepresented or excluded in current available randomized controlled trials and registries. Registration URL: https://www.clinicaltrials.gov; unique identifier: NCT05995561.
DOI:doi:10.1161/JAHA.123.033396
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.1161/JAHA.123.033396
 Volltext: https://www.ahajournals.org/doi/10.1161/JAHA.123.033396
 DOI: https://doi.org/10.1161/JAHA.123.033396
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:1903717418
Verknüpfungen:→ Zeitschrift

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