| |  Online-Ressource |
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| Verfasst von: | Abel, Noah [VerfasserIn]  |
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| | Schupp, Tobias [VerfasserIn] |
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| | Schmitt, Alexander [VerfasserIn] |
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| | Reinhardt, Marielen [VerfasserIn] |
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| | Lau, Felix [VerfasserIn] |
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| | Weidner, Kathrin [VerfasserIn] |
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| | Ayoub, Mohamed [VerfasserIn] |
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| | Mashayekhi, Kambis [VerfasserIn] |
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| | Akın, Ibrahim [VerfasserIn] |
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| | Behnes, Michael [VerfasserIn] |
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| Titel: | Left ventricular diastolic dysfunction in patients with heart failure with mildly reduced ejection fraction |
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| Verf.angabe: | Noah Abel, Tobias Schupp, Alexander Schmitt, Marielen Reinhardt, Felix Lau, Kathrin Weidner, Mohamed Ayoub, Kambis Mashayekhi, Ibrahim Akin, Michael Behnes |
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| E-Jahr: | 2024 |
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| Jahr: | 1 November 2024 |
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| Umfang: | 7 S. |
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| Fussnoten: | Online verfügbar: 28. Juli 2024, Artikelversion: 3. August 2024 ; Gesehen am 25.11.2024 |
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| Titel Quelle: | Enthalten in: International journal of cardiology |
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| Ort Quelle: | Amsterdam [u.a.] : Elsevier Science, 1981 |
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| Jahr Quelle: | 2024 |
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| Band/Heft Quelle: | 414(2024), Artikel-ID 132386, Seite 1-7 |
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| ISSN Quelle: | 1874-1754 |
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| Abstract: | Objective - This study investigates the prevalence and prognostic impact of diastolic dysfunction (DD) in patients hospitalized with heart failure (HF) with mildly reduced ejection fraction (HFmrEF) in sinus rhythm. - Background - Data regarding the prognostic impact of DD in patients with HFmrEF is limited. - Methods - From 2016 to 2022, all patients hospitalized with HFmrEF (i.e., left ventricular ejection fraction 41-49% and signs and/or symptoms of HF) were retrospectively included at one institution. Patients with DD were compared to patients without (i.e., non-DD), further risk stratification was performed according to the severity of DD. The primary endpoint was all-cause mortality at 30 months (interquartile range (IQR) 15-61 months), key secondary endpoint was rehospitalization for worsening HF. - Results - From a total of 1154 patients (median age 68 years, 68% males) hospitalized with HFmrEF, concomitant DD was present in 72% (grade I: 56%, grade II: 14%, grade III: 2%). Patients with DD were older (71 years vs. 65 years; p = 0.001) and presented with higher rates of cardiovascular comorbidities. The presence of DD was not associated with the risk of long-term all-cause mortality (adjusted HR = 0.815; 95% CI 0.612-1.085; p = 0.161) or HF-related rehospitalization (adjusted HR = 0.736; 95% CI 0.442-1.225; p = 0.238). Furthermore, the outcome did not differ in patients with more advanced stages of DD. - Conclusion - DD is commonly prevalent in patients with HFmrEF, but not associated with long-term prognosis. |
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| DOI: | doi:10.1016/j.ijcard.2024.132386 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1016/j.ijcard.2024.132386 |
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| | Volltext: https://www.sciencedirect.com/science/article/pii/S0167527324010088 |
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| | DOI: https://doi.org/10.1016/j.ijcard.2024.132386 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Diastolic dysfunction |
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| | Heart failure with mildly reduced ejection fraction |
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| | HFmrEF |
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| | Mortality |
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| K10plus-PPN: | 1909467871 |
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| Verknüpfungen: | → Zeitschrift |
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Left ventricular diastolic dysfunction in patients with heart failure with mildly reduced ejection fraction / Abel, Noah [VerfasserIn]; 1 November 2024 (Online-Ressource)
