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| Verfasst von: | Benvenuto, Giovanna [VerfasserIn]  |
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| | Leone, Serena [VerfasserIn] |
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| | Astoricchio, Emanuele [VerfasserIn] |
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| | Bormke, Sophia [VerfasserIn] |
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| | Jasek, Sanja [VerfasserIn] |
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| | D'Aniello, Enrico [VerfasserIn] |
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| | Kittelmann, Maike [VerfasserIn] |
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| | McDonald, Kent [VerfasserIn] |
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| | Hartenstein, Volker [VerfasserIn] |
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| | Baena, Valentina [VerfasserIn] |
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| | Escrivà, Héctor [VerfasserIn] |
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| | Bertrand, Stephanie [VerfasserIn] |
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| | Schierwater, Bernd [VerfasserIn] |
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| | Burkhardt, Pawel [VerfasserIn] |
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| | Ruiz-Trillo, Iñaki [VerfasserIn] |
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| | Jékely, Gáspár [VerfasserIn] |
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| | Ullrich-Lüter, Jack [VerfasserIn] |
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| | Lüter, Carsten [VerfasserIn] |
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| | D'Aniello, Salvatore [VerfasserIn] |
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| | Arnone, Maria Ina [VerfasserIn] |
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| | Ferraro, Francesco [VerfasserIn] |
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| Titel: | Evolution of the ribbon-like organization of the Golgi apparatus in animal cells |
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| Verf.angabe: | Giovanna Benvenuto, Serena Leone, Emanuele Astoricchio, Sophia Bormke, Sanja Jasek, Enrico D’Aniello, Maike Kittelmann, Kent McDonald, Volker Hartenstein, Valentina Baena, Héctor Escrivà, Stephanie Bertrand, Bernd Schierwater, Pawel Burkhardt, Iñaki Ruiz-Trillo, Gáspár Jékely, Jack Ullrich-Lüter, Carsten Lüter, Salvatore D’Aniello, Maria Ina Arnone, and Francesco Ferraro |
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| E-Jahr: | 2024 |
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| Jahr: | March 26, 2024 |
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| Umfang: | 22 S. |
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| Fussnoten: | Gesehen am 02.12.2024 |
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| Titel Quelle: | Enthalten in: Cell reports |
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| Ort Quelle: | Maryland Heights, MO : Cell Press, 2012 |
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| Jahr Quelle: | 2024 |
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| Band/Heft Quelle: | 43(2024), 3, Artikel-ID 113791, Seite 113791-1-113791-22 |
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| ISSN Quelle: | 2211-1247 |
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| Abstract: | The "ribbon," a structural arrangement in which Golgi stacks connect to each other, is considered to be restricted to vertebrate cells. Although ribbon disruption is linked to various human pathologies, its functional role in cellular processes remains unclear. In this study, we investigate the evolutionary origin of the Golgi ribbon. We observe a ribbon-like architecture in the cells of several metazoan taxa suggesting its early emergence in animal evolution predating the appearance of vertebrates. Supported by AlphaFold2 modeling, we propose that the evolution of Golgi reassembly and stacking protein (GRASP) binding by golgin tethers may have driven the joining of Golgi stacks resulting in the ribbon-like configuration. Additionally, we find that Golgi ribbon assembly is a shared developmental feature of deuterostomes, implying a role in embryogenesis. Overall, our study points to the functional significance of the Golgi ribbon beyond vertebrates and underscores the need for further investigations to unravel its elusive biological roles. |
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| DOI: | doi:10.1016/j.celrep.2024.113791 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1016/j.celrep.2024.113791 |
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| | Volltext: https://www.sciencedirect.com/science/article/pii/S2211124724001190 |
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| | DOI: https://doi.org/10.1016/j.celrep.2024.113791 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | AlphaFold2 |
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| | development |
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| | evolution |
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| | GM130 |
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| | Golgi ribbon |
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| | Golgi structure |
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| | Golgin-45 |
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| | GRASP |
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| | metazoans |
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| | organelle |
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| K10plus-PPN: | 1910625035 |
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| Verknüpfungen: | → Zeitschrift |
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Evolution of the ribbon-like organization of the Golgi apparatus in animal cells / Benvenuto, Giovanna [VerfasserIn]; March 26, 2024 (Online-Ressource)
