Assessing Human Exposure to Key Chemical Carcinogens

• Verfasst von: Radosavljevic, Vladan [VerfasserIn]
• Titel: Assessing Human Exposure to Key Chemical Carcinogens
• Titelzusatz: Diagnostic Approaches and Interpretation
• Verf.angabe: by Vladan Radosavljevic
• Ausgabe: 1st ed. 2025.
• Verlagsort: Cham
• Verlagsort: Cham
• Verlag: Springer Nature Switzerland
• Verlag: Imprint: Springer
• E-Jahr: 2025
• Jahr: 2025.
• Jahr: 2025.
• Umfang: 1 Online-Ressource(X, 207 p.)
• ISBN: 978-3-031-84441-6
• DOI: doi:10.1007/978-3-031-84441-6
• Datenträger: Online-Ressource
• Sprache: eng
• Bibliogr. Hinweis: Erscheint auch als : Druck-Ausgabe
• Bibliogr. Hinweis: Erscheint auch als : Druck-Ausgabe
• Bibliogr. Hinweis: Erscheint auch als : Druck-Ausgabe
• K10plus-PPN: 1919513647
• K10plus-PPN:
  Universitätsbibliothek
• Lokale URL UB: Zum Volltext
• Lokale URL UB: Bibliothek der Medizinischen Fakultät Mannheim der Universität Heidelberg
• Bibliothek/Idn: UW / m4686047889
• Lokale URL Inst.: Zum Volltext

Abstract

Introduction -- Arsenic -- Cadmium -- Nickel -- Beryllium -- Chromium hexavalent -- Aflatoxins -- 4- Aminobiphenyl -- Aristolochic acids -- Benzene -- Benzidine -- Benzo[a]pyrene.-Bis(chloromethyl) ether (BHME) and Chloromethyl methyl ether (HMME) -- 1,3-Butadiene -- Vinyl chloride -- 1,2-dichloropropane -- Ethylene oxide -- Lindane (gamma hexachlorocyclohexane – γ-HHCH) -- 4,4'-methylenebis(2-chloroaniline) -- 2-naphthylamine (2-NA) -- Orthotoluidine -- Pentachlorophenol -- Polychlorinated biphenyls (PHBs) -- Polycyclic aromatic hydrocarbons (shale oil) -- Polycyclic aromatic hydrocarbons (soot) -- Polycyclic aromatic hydrocarbons (coke production) -- Polycyclic aromatic hydrocarbons (occupational exposure during coal tar distillation) -- Polycyclic aromatic hydrocarbons (emissions from burning coal indoors) -- 2,3,7,8-Tetrachlorodibenzo-para-dioxin -- 2,3,4,7,8-Pentachlorodibenzofuran -- Trichlorethylene.

Abstract

This book introduces an effective, affordable, non-invasive, and quick method to detect exposure to dangerous chemical carcinogens, which cause life-threatening conditions like cardiovascular, endocrine, neurological, hematological, dermatological, and malignant diseases. Nearly 20 million people are diagnosed with cancer annually, with almost 10 million deaths. While eliminating carcinogens completely is impossible, improving detection and monitoring—especially through specialized urine analysis—can help define preventive measures to lower carcinogen levels in the body. The chemical carcinogens discussed have been used for decades without proper evaluation of their health effects, costing millions of lives. Considering the long-term health impacts of current products is critical. Early detection is crucial as most carcinogens have cumulative effects. Identifying urinary markers of exposure can help detect, eliminate, or reduce sources of carcinogens, advancing preventive oncology. The book focuses on Group 1 chemical carcinogens classified by the International Agency for Research on Cancer (IARC). The described methods are highly effective, affordable, and applicable in any location with HPLC (High-Performance Liquid Chromatography) and ICP (Inductively Coupled Plasma) devices. They are non-invasive, requiring only urine samples, quick, and inexpensive. This volume aims to develop, improve, and implement screening methods for malignant diseases. It supports medical professionals in interpreting HPLC and ICP urinary analyses and providing guidance on reducing or avoiding carcinogen exposure. In some cases, doctors may identify sources of exposure and inform authorities to address and eliminate these hazards.