A comparative analysis of the effects of misaligning different trifocal intraocular lenses

• Verfasst von: Yan, Weijia [VerfasserIn]
• Verfasst von: Auffarth, Gerd U. [VerfasserIn]
• Verfasst von: Khoramnia, Ramin [VerfasserIn]
• Verfasst von: Łabuz, Grzegorz [VerfasserIn]
• Titel: A comparative analysis of the effects of misaligning different trifocal intraocular lenses
• Verf.angabe: Weijia Yan, Gerd U. Auffarth, Ramin Khoramnia and Grzegorz Łabuz
• E-Jahr: 2025
• Jahr: January 2025
• Umfang: 11 S.
• Illustrationen: Illustrationen
• Fussnoten: Gesehen am 18.06.2025
• Titel Quelle: Enthalten in: Journal of Clinical Medicine
• Ort Quelle: Basel : MDPI, 2012
• Jahr Quelle: 2025
• Band/Heft Quelle: 14(2025), 1, Artikel-ID 187, Seite 1-11
• ISSN Quelle: 2077-0383
• DOI: doi:10.3390/jcm14010187
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: decentration
• Sach-SW: modulation transfer function
• Sach-SW: optical quality
• Sach-SW: tilt
• Sach-SW: trifocal IOLs
• K10plus-PPN: 1928518680

Abstract

Objectives: This laboratory study aims to assess the effects of misaligning different trifocal intraocular lenses (IOLs) under varying spectral and corneal spherical aberration (SA) conditions. Methods: With an IOL metrology device under monochromatic and polychromatic conditions, the following models were studied: AT ELANA 841P, AT LISA Tri 839MP, FineVision HP POD F, Acrysof IQ PanOptix, and Tecnis Synergy ZFR00V. The SA was simulated using an aberration-free and average-SA cornea. The modulation transfer function (MTF) was measured at different pupil sizes for the on- and off-axis lens positions. Results: The IOLs exhibited varying responses to decentration up to 1 mm, showing the lowest impact in polychromatic light. The least affected was AT ELANA, with an MTF loss of 15.7% to 28.4% at 50 lp/mm across the studied conditions. It was followed by PanOptix and FineVision, with the MTF loss ranging from 19.1% to 36.0% and from 21.2% to 46.6%. AT LISA showed a more substantial reduction, i.e., 41.2% to 64.8%, but it was still lower than that of Synergy (51.1% to 78.8%). When decentration was induced at a 4.5 mm distance, its effect was more evident in conditions that were closer to each IOL’s SA correction. A tilt of 5° had a lesser impact than 1 mm decentration, with the effect being more severe at 4.5 mm. Conclusions: The off-axis position affects the optical quality of trifocal IOLs. Low- rather than high-SA-correcting trifocals perform better under misalignment. In polychromatic light, the impact of misalignment is less evident, suggesting a potential mitigating effect of chromatic aberration.