Frei, Eva Dr. rer. nat.Universität HeidelbergHeidelberg
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Co-Autoren (Uni Heidelberg)
- Brenner, Hermann (1)
- Ulrich, Alexis (1)
- Chang-Claude, Jenny (1)
- Schrotz-King, Petra (1)
- Skender, Stephanie (1)
- Liesenfeld, David (1)
- Kempf, Tore (1)
- Beyerle, Jolantha (1)
- Haffa, Mariam (1)
- Toth, Reka (1)
- Gigić, Biljana (1)
- Schnölzer, Martina (1)
- Seimetz, Diane (1)
- Schneider, Thomas (1)
- Hull, William Edmund (1)
- Weigand, Martina (1)
- Kölsch, Torsten (1)
- Schneider, Martin (1)
- Haefeli, Walter E. (1)
- Becker, Nikolaus (1)
- Herpel, Esther (1)
- Hoffmeister, Michael (1)
- Scherer, Dominique (1)
- Funk, Dorothee (1)
- Edler, Lutz (1)
Co-Autoren (extern)
- Kizek, Rene (2)
- Singh, Rajinder (2)
- Wolf, C. Roland (2)
- Schrenk, Hans-Hermann (2)
- Schmeiser, Heinz H. (2)
- Bárta, František (2)
- Eckschlager, Tomas (2)
- Henderson, Colin J. (2)
- Evans, James D. (2)
- Martinek, Vaclav (2)
- Arlt, Volker M. (2)
- Naiman, Karel (2)
- Levová, Kateřina (2)
- Müller-Ladner, Ulf (1)
- Mareš, Jaroslav (1)
- Hudecek, Jiri (1)
- Böhm, Jürgen (1)
- Trevisan, Maria T.S. (1)
- Klika, Karel D. (1)
- Würtele, Gerd (1)
- Fiehn, Christoph (1)
- Gilberg, Frank (1)
- Neumann, Elena (1)
- Mrízová, Iveta (1)
- Levová, Kateřina (1)
- Hodek, Petr (1)
- Černá, Věra (1)
- Hrabeta, Jan (1)
- Uhlik, Jiri (1)
- Poljakova, Jitka (1)
- Khalil, Mohamed Ashraf (1)
- Groh, Tomas (1)
- Doktorova, Helena (1)
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Publikationen in heiBIB 
- Souza, José R. R. de: Transformation of mangiferin to norathyriol by human fecal matrix in anaerobic conditions : comprehensive NMR of the xanthone metabolites, antioxidant capacity, and comparative cytotoxicity against vancer cell lines / José R.R. Souza, Maria Teresa Salles Trevisan, Judith P.A. Feitosa, Nágila M.P.S. Ricardo, William E… , March 5, 2020. - 9 S.
In: Natural product communications, ISSN 1555-9475. 15(2020), 3, Artikel-ID 1934578X20910286, Seite 1-9
DOI: 10.1177/1934578X20910286
- Beyerle, Jolantha: Expression patterns of xenobiotic-metabolizing enzymes in tumor and adjacent normal mucosa tissues among patients with colorectal cancer : the ColoCare Study / Jolantha Beyerle, Andreana N. Holowatyj, Mariam Haffa, Eva Frei, Biljana Gigic, Petra Schrotz-King, … , 2020. - 10 S.
In: Cancer epidemiology, biomarkers & prevention, ISSN 1538-7755. 29(2020), 2, Seite 460-469
DOI: 10.1158/1055-9965.EPI-19-0449
- Hrabeta, Jan: Vacuolar-ATPase-mediated intracellular sequestration of ellipticine contributes to drug resistance in neuroblastoma cells / Jan Hrabeta, Tomas Groh, Mohamed Ashraf Khalil, Jitka Poljakova, Vojtech Adam, Rene Kizek, Jiri Uhli… , June 29, 2015. - 10 S.
In: International journal of oncology, ISSN 1791-2423. 47(2015), 3, Seite 971-980
DOI: 10.3892/ijo.2015.3066
- Arlt, Volker M.: Pulmonary inflammation impacts on CYP1A1-mediated respiratory tract DNA damage induced by the carcinogenic air pollutant benzo[a]pyrene / Volker M. Arlt, Annette M. Krais, Roger W. Godschalk, Yanira Riffo-Vasquez, Iveta Mrizova, Candice A… , April 23, 2015. - 13 S.
In: Toxicological sciences, ISSN 1096-0929. 146(2015), 2, Seite 213-225
DOI: 10.1093/toxsci/kfv086
- Beyerle, Jolantha: Biotransformation of xenobiotics in the human colon and rectum and its association with colorectal cancer / Jolantha Beyerle, Eva Frei, Marie Stiborova, Nina Habermann, Cornelia M. Ulrich, 17 Feb 2015. - 23 S.
In: Drug metabolism reviews, ISSN 1097-9883. 47(2015), 2, Seite 199-221
DOI: 10.3109/03602532.2014.996649
- Liesenfeld, David: Changes in urinary metabolic profiles of colorectal cancer patients enrolled in a prospective cohort study (ColoCare) / David B. Liesenfeld, Nina Habermann, Reka Toth, Robert W. Owen, Eva Frei, Jürgen Böhm, Petra Schrotz… , 2015. - 15 S.
In: Metabolomics, ISSN 1573-3890. 11(2015), 4, Seite 998-1012
DOI: 10.1007/s11306-014-0758-3
- Stiborová, Marie: The anticancer drug ellipticine activated with cytochrome P450 mediates DNA damage determining its pharmacological efficiencies : studies with rats, hepatic cytochrome P450 reductase null (HRN™) mice and pure enzymes / Marie Stiborová, Věra Černá, Michaela Moserová, Iveta Mrízová, Volker M. Arlt, Eva Frei, 2015. - 23 S.
In: International journal of molecular sciences, ISSN 1422-0067. 16(2015), 1, Seite 284-306
DOI: 10.3390/ijms16010284
- Stiborová, Marie: The influence of ochratoxin A on DNA adduct formation by the carcinogen aristolochic acid in rats / Marie Stiborová, František Bárta, Kateřina Levová, Petr Hodek, Eva Frei, Volker M. Arlt, Heinz H. Sc… , 2015. - 18 S.
In: Archives of toxicology, ISSN 1432-0738. 89(2015), 11, Seite 2141-2158
DOI: 10.1007/s00204-014-1360-1
- Funk, Dorothee: Development of a novel polyethylene glycol-corticosteroid-conjugate with an acid-cleavable linker / Dorothee Funk, Hans-Hermann Schrenk & Eva Frei, 2011. - 12 S.
In: Journal of drug targeting, ISSN 1029-2330. 19(2011), 6, Seite 434-445
DOI: 10.3109/1061186X.2010.504271
- Frei, Eva: Albumin binding ligands and albumin conjugate uptake by cancer cells / Eva Frei, 15 June 2011. - 4 S.
In: Diabetology & metabolic syndrome, ISSN 1758-5996. 3(2011), Artikel-ID 11, Seite 1-4
DOI: 10.1186/1758-5996-3-11
- Poljakova, Jitka: Anticancer agent ellipticine combined with histone deacetylase inhibitors, valproic acid and trichostatin A, is an effective DNA damage strategy in human neuroblastoma / Jitka Poljakova, Jana Hrebackova, Marketa Dvorakova, Michaela Moserova, Tomas Eckschlager, Jan Hrabe… , 05 November 2011. - 16 S.
In: Neuroendocrinology letters, ISSN 2354-4716. 32(2011), Suppl 1, Seite 101-116
- Stiborová, Marie: Role of cytochromes P450 in metabolism of carcinogenic aristolochic acid I : evidence of their contribution to aristolochic acid I detoxication and activation in rat liver / Marie Stiborova, Jaroslav Mares, Kateřina Levova, Jana Pavlickova, Frantisek Barta, Petr Hodek, Eva … , 2011. - 10 S.
In: Neuroendocrinology letters, ISSN 2354-4716. 32(2011), 1, Seite 121-130
- Stiborová, Marie: The human carcinogen aristolochic acid i is activated to form DNA adducts by human NAD(P)H : quinone oxidoreductase without the contribution of acetyltransferases or sulfotransferases / Marie Stiborová, Jaroslav Mareîs, Eva Frei, Volker M. Arlt, Václav Martínek, and Heinz H. Schmeiser, 02 March 2011. - 12 S.
In: Environmental and molecular mutagenesis, ISSN 1098-2280. 52(2011), 6, Seite 448-459
DOI: 10.1002/em.20642
- Naiman, Karel: Human cytochrome-P450 enzymes metabolize N-(2-methoxyphenyl)hydroxylamine, a metabolite of the carcinogens o-anisidine and o-nitroanisole, thereby dictating its genotoxicity / Karel Naiman, Markéta Martínková, Heinz H. Schmeiser, Eva Frei, Marie Stiborová, 17 September 2011. - 9 S.
In: Mutation research, ISSN 1388-2120. 726(2011), 2, Seite 160-168
DOI: 10.1016/j.mrgentox.2011.09.010
- Levová, Kateřina: Role of pytochromes P450 1A1/2 in detoxication and activation of carcinogenic aristolochic acid I : studies with the hepatic NADPH:Cytochrome P450 reductase null (HRN) mouse model / Kateřina Levová, Michaela Moserová, Věra Kotrbová, Miroslav Šulc, Colin J. Henderson, C. Roland Wolf… , 2011. - 14 S.
In: Toxicological sciences, ISSN 1096-0929. 121(2011), 1, Seite 43-56
DOI: 10.1093/toxsci/kfr050
- Martinek, Vaclav: Comparison of activation of aristolochic acid I and II with NADPH : quinone oxidoreductase, sulphotransferases and N-acetyltranferases / Vaclav Martinek, Bozena Kubickova, Volker M. Arlt, Eva Frei, Heinz H. Schmeiser, Jiri Hudecek, Marie… , 2011-11-05. - 14 S.
In: Neuroendocrinology letters, ISSN 2354-4716. 32(2011), 1, Seite 57-70
- Hodek, Petr: Impact of beta-naphthoflavone on genotoxicity of food-derived carcinogens / Petr Hodek, Jitka Krizkova, Eva Frei, Rajinder Singh, Volker M. Arlt, Marie Stiborova, [2011]. - 10 S. : Diagramme
In: Neuroendocrinology letters, ISSN 2354-4716. 32(2011), Suppl. 1, Seite 25-34
- Kotrbová, Věra: Cytochrome b5 shifts oxidation of the anticancer drug ellipticine by cytochromes P450 1A1 and 1A2 from its detoxication to activation, thereby modulating its pharmacological efficacy / Věra Kotrbová, Barbora Mrázová, Michaela Moserová, Václav Martínek, Petr Hodek, Jiří Hudeček, Eva Fr… , 13 June 2011. - 12 S.
In: Biochemical pharmacology, ISSN 1873-2968. 82(2011), 6, Seite 669-680
DOI: 10.1016/j.bcp.2011.06.003
- Ding, Reinhard: Pharmacokinetics of 5-Aminofluorescein-Albumin, a novel fluorescence marker of brain tumors during surgery / Reinhard Ding, Eva Frei, Mahmoudreza Fardanesh, Hans-Hermann Schrenk, Paul Kremer, and Walter E. Hae… , 2011. - 7 S.
In: Journal of clinical pharmacology, ISSN 1552-4604. 51(2011), 5, Seite 672-678
DOI: 10.1177/0091270010372626
- Arlt, Volker M.: Effect of hepatic cytochrome P450 (P450) oxidoreductase deficiency on 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-DNA adduct formation in P450 reductase conditional null mice / Volker M. Arlt, Rajinder Singh, Marie Stiborová, Gonçalo Gamboa da Costa, Eva Frei, James D. Evans, … , November 21, 2011. - 5 S.
In: Drug metabolism and disposition, ISSN 1521-009X. 39(2011), 12, Seite 2169-2173
DOI: 10.1124/dmd.111.041343
- Arlt, Volker M.: Role of P450 1A1 and P450 1A2 in bioactivation versus detoxication of the renal carcinogen aristolochic acid I : studies in Cyp1a1(−/−), Cyp1a2(−/−), and Cyp1a1/1a2(−/−) mice / Volker M. Arlt, Kateřina Levová, František Bárta, Zhanquan Shi, James D. Evans, Eva Frei, Heinz H. S… , 29 September 2011. - 10 S.
In: Chemical research in toxicology, ISSN 1520-5010. 24(2011), 10, Seite 1710-1719
DOI: 10.1021/tx200259y
- Neumann, Elena: Native albumin for targeted drug delivery / Elena Neumann, Eva Frei, Dorothee Funk, Matthias D Becker, Hans-Hermann Schrenk, Ulf Müller-Ladner &… , 30 Jun 2010. - 11 S.
In: Expert opinion on drug delivery, ISSN 1744-7593. 7(2010), 8, Seite 915-925
DOI: 10.1517/17425247.2010.498474
- Naiman, Karel: Rat liver microsomal metabolism of o-aminophenol and N-(2-methoxyphenyl)hydroxylamine, two metabolites of the environmental pollutant and carcinogen o-anisidine in humans / Karel Naiman, Petr Hodek, Jiří Liberda, Heinz H. Schmeiser, Eva Frei and Marie Stiborová, 2010-11-18. - 19 S.
In: Collection of Czechoslovak chemical communications, ISSN 1212-6950. 75(2010), 12, Seite 1229-1247
DOI: 10.1135/cccc2010077
- Frei, Eva: Analysis of the inhibition of N-nitroso-dimethylamine activation in the liver by N-nitro-dimethylamine using a new non-linear statistical method / Eva Frei, Frank Gilberg, Manuela Schröder, Andrea Breuer, Lutz Edler and Manfred Wiessler, 01 March 1999. - 6 S.
In: Carcinogenesis, ISSN 1460-2180. 20(1999), 3, Seite 459-464
DOI: 10.1093/carcin/20.3.459
- Schneider, Thomas: The profile of urinary metabolites of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in rats is determined by its pulmonary metabolism / Thomas Schneider, Eva Frei, Manfred Wiessler, 22 April 1999. - 20 S.
In: Chemico-biological interactions, ISSN 1872-7786. 118(1999), 3, Seite 247-266
DOI: 10.1016/S0009-2797(99)00083-6
- Seimetz, Diane: One step isolation of bovine asialoglycoprotein receptor and its characterization by sequence analysis and MALDI mass spectrometry / Diane Seimetz, Eva Frei, Martina Schnölzer, Tore Kempf, and Manfred Wiessler, 1999. - 10 S.
In: Bioscience reports, ISSN 1573-4935. 19(1999), 2, Seite 115-124
DOI: 10.1023/A:1020162527447
- Weigand, Martina: Mechanisms of resistance to methotrexate in childhood acute lymphoblastic leukemia : circumvention of thymidylate synthase inhibition / M. Weigand, E. Frei, N. Graf, B. Buchholz, C. Wolfrom, A. Breuer, M. Wiessler, 1999. - 7 S.
In: Journal of cancer research and clinical oncology, ISSN 1432-1335. 125(1999), 8, Seite 513-519
DOI: 10.1007/s004320050310
