Status: Bibliographieeintrag
Standort: ---
Exemplare:
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| Online-Ressource |
Verfasst von: | Grübler, Martin R. [VerfasserIn]  |
| März, Winfried [VerfasserIn]  |
Titel: | Effects of vitamin D supplementation on plasma aldosterone and renin |
Titelzusatz: | a randomized placebo-controlled trial |
Verf.angabe: | Martin R. Grübler, Martin Gaksch, Katharina Kienreich, Nicolas Verheyen, Johannes Schmid, Bríain W. J. Ó Hartaigh, Georg Richtig, Hubert Scharnagl, Andreas Meinitzer, Burkert Pieske, Astrid Fahrleitner‐Pammer, Winfried März, Andreas Tomaschitz, Stefan Pilz |
E-Jahr: | 2016 |
Jahr: | 21 April 2016 |
Umfang: | 6 S. |
Fussnoten: | Gesehen am 11.03.2020 |
Titel Quelle: | Enthalten in: The journal of clinical hypertension |
Ort Quelle: | Hoboken, NJ : Wiley, 2001 |
Jahr Quelle: | 2016 |
Band/Heft Quelle: | 18(2016), 7, Seite 608-613 |
ISSN Quelle: | 1751-7176 |
Abstract: | Increasing evidence describes a possible interplay between vitamin D insufficiency with increased aldosterone. The authors sought to evaluate the effect of vitamin D supplementation on plasma aldosterone concentration (PAC) in patients with hypertension and 25-hydroxyvitamin D[25(OH)D] insufficiency. The Styrian Vitamin D Hypertension Trial was a single-center, double-blind, placebo-controlled randomized clinical trial conducted from 2011 to 2014. Two hundred patients with arterial hypertension and 25(OH)D levels <30 ng/mL were enrolled. Study participants were randomized to receive either 2800 IU of vitamin D3 or placebo. The present investigation is a post hoc analysis using analysis of covariance adjusting for baseline differences. A total of 188 participants (mean±standard deviation age, 60.1±11.3 years; 47% women; 25(OH)D, 21.2±5.6 ng/mL) completed the trial. Mean differences between baseline and follow-up PAC in the control and intervention arm were +3.3 ng/dL and +0.9 ng/dL, respectively (P=.04). The findings indicate that vitamin D3 supplementation significantly decreases PAC in patients with arterial hypertension and 25(OH)D insufficiency. |
DOI: | doi:10.1111/jch.12825 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1111/jch.12825 |
| Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1111/jch.12825 |
| DOI: https://doi.org/10.1111/jch.12825 |
Datenträger: | Online-Ressource |
Sprache: | eng |
K10plus-PPN: | 1692278916 |
Verknüpfungen: | → Zeitschrift |
Effects of vitamin D supplementation on plasma aldosterone and renin / Grübler, Martin R. [VerfasserIn]; 21 April 2016 (Online-Ressource)
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